RgpA-Kgp Peptide-Based Immunogens Provide Protection against Porphyromonas gingivalis Challenge in a Murine Lesion Model

Por O'Brien-Simpson, Neil M., Paolini, Rita A., Reynolds, Eric C.
Publicado em 2000

Editorial: Antimicrobial and Anticancer Peptides

Por O'Brien-Simpson, Neil M., Hoffmann, Ralf, Chia, C. S. Brian, Wade, John D.
Publicado no Front Chem (2018)

Outer Membrane Vesicle-Host Cell Interactions

Por Cecil, Jessica D., Sirisaengtaksin, Natalie, O’Brien-Simpson, Neil M., Krachler, Anne Marie
Publicado no Microbiol Spectr (2019)

Porphyromonas gingivalis RgpA-Kgp Proteinase-Adhesin Complexes Penetrate Gingival Tissue and Induce Proinflammatory Cytokines or Apoptosis in a Concentration-Dependent Manner

Por O'Brien-Simpson, Neil M., Pathirana, Rishi D., Walker, Glenn D., Reynolds, Eric C.
Publicado em 2009

Immunization with the RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Protects against Periodontal Bone Loss in the Rat Periodontitis Model

Por Rajapakse, P. Sunethra, O'Brien-Simpson, Neil M., Slakeski, Nada, Hoffmann, Brigitte, Reynolds, Eric C.
Publicado em 2002

Kgp and RgpB, but Not RgpA, Are Important for Porphyromonas gingivalis Virulence in the Murine Periodontitis Model

Por Pathirana, Rishi D., O'Brien-Simpson, Neil M., Brammar, Gail C., Slakeski, Nada, Reynolds, Eric C.
Publicado em 2007

Flow Cytometric Analysis of Adherence of Porphyromonas gingivalis to Oral Epithelial Cells

Por Pathirana, Rishi D., O'Brien-Simpson, Neil M., Visvanathan, Kumar, Hamilton, John A., Reynolds, Eric C.
Publicado em 2007

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

Por O'Brien-Simpson, Neil M., Burgess, Kate, Brammar, Gail C., Darby, Ivan B., Reynolds, Eric C.
Publicado no J Oral Microbiol (2015)

A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

Por O’Brien-Simpson, Neil M., Pantarat, Namfon, Attard, Troy J., Walsh, Katrina A., Reynolds, Eric C.
Publicado no PLoS One (2016)

Determination of Active Phagocytosis of Unopsonized Porphyromonas gingivalis by Macrophages and Neutrophils Using the pH-Sensitive Fluorescent Dye pHrodo

Por Lenzo, Jason C., O'Brien-Simpson, Neil M., Cecil, Jessica, Holden, James A., Reynolds, Eric C.
Publicado no Infect Immun (2016)

Role of RgpA, RgpB, and Kgp Proteinases in Virulence of Porphyromonas gingivalis W50 in a Murine Lesion Model

Por O'Brien-Simpson, Neil M., Paolini, Rita A., Hoffmann, Brigitte, Slakeski, Nada, Dashper, Stuart G., Reynolds, Eric C.
Publicado em 2001

The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

Por Tam, Vivian, O'Brien-Simpson, Neil M., Chen, Yu-Yen, Sanderson, Colin J., Kinnear, Beverley, Reynolds, Eric C.
Publicado em 2009

Prospects for treatment of Porphyromonas gingivalis-mediated disease – immune-based therapy

Por Reynolds, Eric C., O'Brien-Simpson, Neil, Rowe, Tony, Nash, Andrew, McCluskey, Jackie, Vingadassalom, Didier, Kleanthous, Harold
Publicado no J Oral Microbiol (2015)

(Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members

Por Welch, Nicholas G., Li, Wenyi, Hossain, Mohammed Akhter, Separovic, Frances, O'Brien-Simpson, Neil M., Wade, John D.
Publicado no Front Chem (2020)

Porphyromonas gingivalis Lipopolysaccharide Weakly Activates M1 and M2 Polarized Mouse Macrophages but Induces Inflammatory Cytokines

Por Holden, James A., Attard, Troy J., Laughton, Katrina M., Mansell, Ashley, O'Brien-Simpson, Neil M., Reynolds, Eric C.
Publicado em 2014

Unprimed, M1 and M2 Macrophages Differentially Interact with Porphyromonas gingivalis

Por Lam, Roselind S., O’Brien-Simpson, Neil M., Holden, James A., Lenzo, Jason C., Fong, Shao B., Reynolds, Eric C.
Publicado no PLoS One (2016)

Porphyromonas gulae Has Virulence and Immunological Characteristics Similar to Those of the Human Periodontal Pathogen Porphyromonas gingivalis

Por Lenzo, Jason C., O'Brien-Simpson, Neil M., Orth, Rebecca K., Mitchell, Helen L., Dashper, Stuart G., Reynolds, Eric C.
Publicado no Infect Immun (2016)

Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2

Por Holden, James A., O'Brien-Simpson, Neil M., Lenzo, Jason C., Orth, Rebecca K. H., Mansell, Ashley, Reynolds, Eric C.
Publicado no Infect Immun (2017)

Kappacin, a Novel Antibacterial Peptide from Bovine Milk

Por Malkoski, Marina, Dashper, Stuart G., O'Brien-Simpson, Neil M., Talbo, Gert H., Macris, Mary, Cross, Keith J., Reynolds, Eric C.
Publicado em 2001

Serum Immunoglobulin G (IgG) and IgG Subclass Responses to the RgpA-Kgp Proteinase-Adhesin Complex of Porphyromonas gingivalis in Adult Periodontitis

Por O'Brien-Simpson, Neil M., Black, Catherine L., Bhogal, Peter S., Cleal, Steven M., Slakeski, Nada, Higgins, Thomas J., Reynolds, Eric C.
Publicado em 2000