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Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2

Porphyromonas gulae is an anaerobic, Gram-negative coccobacillus that has been associated with periodontal disease in companion animals. The aims of this study were to analyze the ligation of pattern recognition receptors by P. gulae and the subsequent activation of macrophages. Exposure of HEK cell...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Holden, James A., O'Brien-Simpson, Neil M., Lenzo, Jason C., Orth, Rebecca K. H., Mansell, Ashley, Reynolds, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563586/
https://ncbi.nlm.nih.gov/pubmed/28630066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00282-17
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