“Human Brain Development through the Lens of Cerebral Organoid Models”

por Andrews, Madeline G., Nowakowski, Tomasz J.
Publicado en Brain Res (2019)

Identification of cell types in a mouse brain single-cell atlas using low sampling coverage

por Bhaduri, Aparna, Nowakowski, Tomasz J, Pollen, Alex A, Kriegstein, Arnold R
Publicado en BMC Biol (2018)

Are Organoids Ready for Prime Time?

por Bhaduri, Aparna, Andrews, Madeline G., Kriegstein, Arnold R., Nowakowski, Tomasz J.
Publicado en Cell Stem Cell (2020)

Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development

por Nowakowski, Tomasz J., Pollen, Alex A., Sandoval-Espinosa, Carmen, Kriegstein, Arnold R.
Publicado en Neuron (2016)

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

por Eze, Ugomma C., Bhaduri, Aparna, Haeussler, Maximilian, Nowakowski, Tomasz J., Kriegstein, Arnold R.
Publicado en Nat Neurosci (2021)

Novel lines of Pax6(-/- )embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

por Quinn, Jane C, Molinek, Michael, Nowakowski, Tomasz J, Mason, John O, Price, David J
Publicado 2010

The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells

por Gambardella, Gennaro, Carissimo, Annamaria, Chen, Amy, Cutillo, Luisa, Nowakowski, Tomasz J., di Bernardo, Diego, Blelloch, Robert
Publicado en Nat Commun (2017)

Radial glia require PDGFD/PDGFRß signaling in human but not mouse neocortex

por Lui, Jan H., Nowakowski, Tomasz J., Pollen, Alex A., Javaherian, Ashkan, Kriegstein, Arnold R., Oldham, Michael C.
Publicado en Nature (2014)

A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA

por Rani, Neha, Nowakowski, Tomasz J, Zhou, Hongjun, Godshalk, Sirie E., Lisi, Véronique, Kriegstein, Arnold R., Kosik, Kenneth S.
Publicado en Neuron (2016)

Human iPSC-derived cerebral organoids model cellular features of lissencephaly and reveal prolonged mitosis of outer radial glia

por Bershteyn, Marina, Nowakowski, Tomasz J., Pollen, Alex A., Di Lullo, Elizabeth, Nene, Aishwarya, Wynshaw-Boris, Anthony, Kriegstein, Arnold R.
Publicado en Cell Stem Cell (2017)

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo

por Pratt, Thomas, Davey, John W, Nowakowski, Tomasz J, Raasumaa, Casey, Rawlik, Konrad, McBride, Derek, Clinton, Michael, Mason, John O, Price, David J
Publicado 2012

The Expanding Cell Diversity of the Brain Vasculature

por Ross, Jayden M., Kim, Chang, Allen, Denise, Crouch, Elizabeth E., Narsinh, Kazim, Cooke, Daniel L., Abla, Adib A., Nowakowski, Tomasz J., Winkler, Ethan A.
Publicado en Front Physiol (2020)

Transcriptional fates of human-specific segmental duplications in brain

por Dougherty, Max L., Underwood, Jason G., Nelson, Bradley J., Tseng, Elizabeth, Munson, Katherine M., Penn, Osnat, Nowakowski, Tomasz J., Pollen, Alex A., Eichler, Evan E.
Publicado en Genome Res (2018)

Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration

por Linsley, Jeremy W., Tripathi, Atmiyata, Epstein, Irina, Schmunk, Galina, Mount, Elliot, Campioni, Matthew, Oza, Viral, Barch, Mariya, Javaherian, Ashkan, Nowakowski, Tomasz J., Samsi, Siddharth, Finkbeiner, Steven
Publicado en Commun Biol (2019)

Single‐cell sequencing maps gene expression to mutational phylogenies in PDGF‐ and EGF‐driven gliomas

por Müller, Sören, Liu, Siyuan John, Di Lullo, Elizabeth, Malatesta, Martina, Pollen, Alex A, Nowakowski, Tomasz J, Kohanbash, Gary, Aghi, Manish, Kriegstein, Arnold R, Lim, Daniel A, Diaz, Aaron
Publicado en Mol Syst Biol (2016)

A Chromatin Accessibility Atlas of the Developing Human Telencephalon

por Markenscoff-Papadimitriou, Eirene, Whalen, Sean, Przytycki, Pawel, Thomas, Reuben, Binyameen, Fadya, Nowakowski, Tomasz J., Kriegstein, Arnold R., Sanders, Stephan J., State, Matthew W., Pollard, Katherine S., Rubenstein, John L.
Publicado en Cell (2020)

Regulation of Cell-Type-Specific Transcriptomes by miRNA Networks During Human Brain Development

por Nowakowski, Tomasz J, Rani, Neha, Golkaram, Mahdi, Zhou, Hongjun R, Alvarado, Beatriz, Huch, Kylie, West, Jay A, Leyrat, Anne, Pollen, Alex A, Kriegstein, Arnold R, Petzold, Linda R, Kosik, Kenneth S.
Publicado en Nat Neurosci (2018)

Cell Stress in Cortical Organoids Impairs Molecular Subtype Specification

por Bhaduri, Aparna, Andrews, Madeline G., Mancia, Walter, Jung, Diane, Shin, David, Allen, Denise, Jung, Dana, Schmunk, Galina, Haeussler, Maximilian, Salma, Jahan, Pollen, Alex A., Nowakowski, Tomasz J., Kriegstein, Arnold R.
Publicado en Nature (2020)

Single-cell analysis of long non-coding RNAs in the developing human neocortex

por Liu, Siyuan John, Nowakowski, Tomasz J., Pollen, Alex A., Lui, Jan H., Horlbeck, Max A., Attenello, Frank J., He, Daniel, Weissman, Jonathan S., Kriegstein, Arnold R., Diaz, Aaron A., Lim, Daniel A.
Publicado en Genome Biol (2016)

Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing

por Adorjan, Istvan, Tyler, Teadora, Bhaduri, Aparna, Demharter, Samuel, Finszter, Cintia Klaudia, Bako, Maria, Sebok, Oliver Marcell, Nowakowski, Tomasz J., Khodosevich, Konstantin, Møllgård, Kjeld, Kriegstein, Arnold R., Shi, Lei, Hoerder‐Suabedissen, Anna, Ansorge, Olaf, Molnár, Zoltán
Publicado en J Anat (2019)