Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration

Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and are amenable to microscopy, but established te...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Linsley, Jeremy W., Tripathi, Atmiyata, Epstein, Irina, Schmunk, Galina, Mount, Elliot, Campioni, Matthew, Oza, Viral, Barch, Mariya, Javaherian, Ashkan, Nowakowski, Tomasz J., Samsi, Siddharth, Finkbeiner, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494885/
https://ncbi.nlm.nih.gov/pubmed/31069265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0411-9
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