Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration

Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and are amenable to microscopy, but established te...

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Опубликовано в: :Commun Biol
Главные авторы: Linsley, Jeremy W., Tripathi, Atmiyata, Epstein, Irina, Schmunk, Galina, Mount, Elliot, Campioni, Matthew, Oza, Viral, Barch, Mariya, Javaherian, Ashkan, Nowakowski, Tomasz J., Samsi, Siddharth, Finkbeiner, Steven
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494885/
https://ncbi.nlm.nih.gov/pubmed/31069265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0411-9
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