The immune system

Por Nicholson, Lindsay B.
Publicado no Essays Biochem (2016)

A simple immune system simulation reveals optimal movement and cell density parameters for successful target clearance

Por Nicholson, David, Nicholson, Lindsay B
Publicado em 2008

The adaptive immune system in diseases of the central nervous system

Por Wraith, David C., Nicholson, Lindsay B.
Publicado em 2012

Autopathogenic T Helper Cell Type 1 (Th1) and Protective Th2 Clones Differ in Their Recognition of the Autoantigenic Peptide of Myelin Proteolipid Protein

Por Das, Mercy Prabhu, Nicholson, Lindsay B., Greer, Judith M., Kuchroo, Vijay K.
Publicado em 1997

A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens

Por Nicholson, Lindsay B., Murtaza, Anwar, Hafler, Brian P., Sette, Alessandro, Kuchroo, Vijay K.
Publicado em 1997

Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: Implications for autoimmunity

Por Nicholson, Lindsay B., Waldner, Hanspeter, Carrizosa, Ana M., Sette, Alessandro, Collins, Mary, Kuchroo, Vijay K.
Publicado em 1998

Reduced Self-Reactivity of an Autoreactive T Cell After Activation with Cross-reactive Non–Self-Ligand

Por Munder, Markus, Bettelli, Estelle, Monney, Laurent, Slavik, Jacqueline M., Nicholson, Lindsay B., Kuchroo, Vijay K.
Publicado em 2002

High Frequency of Autoreactive Myelin Proteolipid Protein–Specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-Reactive Repertoire

Por Anderson, Ana C., Nicholson, Lindsay B., Legge, Kevin L., Turchin, Vadim, Zaghouani, Habib, Kuchroo, Vijay K.
Publicado em 2000

TNFR1 signalling is a critical checkpoint for developing macrophages that control of T-cell proliferation

Por Raveney, Ben J E, Copland, David A, Calder, Claudia J, Dick, Andrew D, Nicholson, Lindsay B
Publicado em 2010

Therapeutic dosing of FTY720 (Fingolimod) prevents cell infiltrate, rapidly suppresses ocular inflammation and maintains blood-ocular barrier

Por Copland, David A., Liu, Jian, Schewitz-Bowers, Lauren, Brinkmann, Volker, Anderson, Karen, Nicholson, Lindsay B., Dick, Andrew D.
Publicado em 2011

Autoimmune and autoinflammatory mechanisms in uveitis

Por Lee, Richard W., Nicholson, Lindsay B., Sen, H. Nida, Chan, Chi-Chao, Wei, Lai, Nussenblatt, Robert B., Dick, Andrew D.
Publicado em 2014

A novel pathogenic RBP-3 peptide reveals epitope spreading in persistent experimental autoimmune uveoretinitis

Por Boldison, Joanne, Khera, Tarnjit K, Copland, David A, Stimpson, Madeleine L, Crawford, Gemma L, Dick, Andrew D, Nicholson, Lindsay B
Publicado no Immunology (2015)

Environmental conditioning in the control of macrophage thrombospondin-1 production

Por Fordham, Jezrom B., Hua, Jing, Morwood, Sarah R., Schewitz-Bowers, Lauren P., Copland, David A., Dick, Andrew D., Nicholson, Lindsay B.
Publicado em 2012

Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Por Boldison, Joanne, Chu, Colin J., Copland, David A., Lait, Philippa J. P., Khera, Tarnjit K., Dick, Andrew D., Nicholson, Lindsay B.
Publicado em 2014

Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis

Por Liu, Jian, Copland, David A., Theodoropoulou, Sofia, Chiu, Hsi An Amy, Barba, Miriam Durazo, Mak, Ka Wang, Mack, Matthias, Nicholson, Lindsay B., Dick, Andrew D.
Publicado no Sci Rep (2016)

Monoclonal Antibody-Mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis

Por Copland, David A., Calder, Claudia J., Raveney, Ben J.E., Nicholson, Lindsay B., Phillips, Joseph, Cherwinski, Holly, Jenmalm, Maria, Sedgwick, Jonathon D., Dick, Andrew D.
Publicado em 2007

Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in...

Por Liu, Jian, Copland, David A., Horie, Shintaro, Wu, Wei-Kang, Chen, Mei, Xu, Yunhe, Paul Morgan, B., Mack, Matthias, Xu, Heping, Nicholson, Lindsay B., Dick, Andrew D.
Publicado em 2013

CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization

Por Horie, Shintaro, Robbie, Scott J., Liu, Jian, Wu, Wei-Kang, Ali, Robin R., Bainbridge, James W., Nicholson, Lindsay B., Mochizuki, Manabu, Dick, Andrew D., Copland, David A.
Publicado em 2013