Cancer targeting vaccines:   Surrogate measures of activity

von Nemunaitis, John J.
Veröffentlicht 2013

Nucleic acid aptamers for targeting of shRNA-based cancer therapeutics

von Vorhies, John S, Nemunaitis, John J
Veröffentlicht 2007

Liposomal insulin promoter–thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice

von Wu, James X., Liu, Shi-He, Nemunaitis, John J., Brunicardi, F. Charles
Veröffentlicht in Cancer Lett (2015)

Analysis of Adenoviral p53 Gene Therapy Clinical Trials in Recurrent Head and Neck Squamous Cell Carcinoma

von Sobol, Robert E., Menander, Kerstin B., Chada, Sunil, Wiederhold, Dora, Sellman, Beatha, Talbott, Max, Nemunaitis, John J.
Veröffentlicht in Front Oncol (2021)

Regulated intratumoral expression of IL-12 as a basis for combination therapy in melanoma

von Nemunaitis, John J, Linette, Gerald P, Hamid, Omid, Agarwala, Sanjiv S, Starodub, Alexander, Sun, Lei, Lebel, Francois, Barrett, John A, Lewis, Jonathan
Veröffentlicht 2014

A first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignancies

von Nemunaitis, John J, Small, Karen A, Kirschmeier, Paul, Zhang, Da, Zhu, Yali, Jou, Ying-Ming, Statkevich, Paul, Yao, Siu-Long, Bannerji, Rajat
Veröffentlicht 2013

Resident Memory T Cells and Their Effect on Cancer

von Craig, Daniel J., Creeden, Justin F., Einloth, Katelyn R., Gillman, Cassidy E., Stanbery, Laura, Hamouda, Danae, Edelman, Gerald, Dworkin, Lance, Nemunaitis, John J.
Veröffentlicht in Vaccines (Basel) (2020)

Phase 2 trial of erlotinib with or without PF-3512676 (CPG 7909, a Toll-like receptor 9 agonist) in patients with advanced recurrent EGFR-positive non-small cell lung cancer

von Belani, Chandra P, Nemunaitis, John J, Chachoua, Abraham, Eisenberg, Peter D, Raez, Luiz E, Cuevas, J Daniel, Mather, Cecile B, Benner, Rebecca J, Meech, Sandra J
Veröffentlicht 2013

Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer

von Hege, Kristen M., Bergsland, Emily K., Fisher, George A., Nemunaitis, John J., Warren, Robert S., McArthur, James G., Lin, Andy A., Schlom, Jeffrey, June, Carl H., Sherwin, Stephen A.
Veröffentlicht in J Immunother Cancer (2017)

Cutaneous head and neck melanoma in OPTiM, a randomized phase 3 trial of talimogene laherparepvec versus granulocyte‐macrophage colony‐stimulating factor for the treatment of unres...

von Andtbacka, Robert H. I., Agarwala, Sanjiv S., Ollila, David W., Hallmeyer, Sigrun, Milhem, Mohammed, Amatruda, Thomas, Nemunaitis, John J., Harrington, Kevin J., Chen, Lisa, Shilkrut, Mark, Ross, Merrick, Kaufman, Howard L.
Veröffentlicht in Head Neck (2016)

First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer pati...

von Berinstein, Neil L, Karkada, Mohan, Morse, Michael A, Nemunaitis, John J, Chatta, Gurkamal, Kaufman, Howard, Odunsi, Kunle, Nigam, Rita, Sammatur, Leeladhar, MacDonald, Lisa D, Weir, Genevieve M, Stanford, Marianne M, Mansour, Marc
Veröffentlicht 2012

Avelumab in patients with previously treated metastatic melanoma: phase 1b results from the JAVELIN Solid Tumor trial

von Keilholz, Ulrich, Mehnert, Janice M., Bauer, Sebastian, Bourgeois, Hugues, Patel, Manish R., Gravenor, Donald, Nemunaitis, John J., Taylor, Matthew H., Wyrwicz, Lucjan, Lee, Keun-Wook, Kasturi, Vijay, Chin, Kevin, von Heydebreck, Anja, Gulley, James L.
Veröffentlicht in J Immunother Cancer (2019)

First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody–Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors

von Hassan, Raffit, Blumenschein, George R., Moore, Kathleen N., Santin, Alessandro D., Kindler, Hedy L., Nemunaitis, John J., Seward, Shelly M., Thomas, Anish, Kim, Stella K., Rajagopalan, Prabhu, Walter, Annette O., Laurent, Dirk, Childs, Barrett H., Sarapa, Nenad, Elbi, Cem, Bendell, Johanna C.
Veröffentlicht in J Clin Oncol (2020)

Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine...

von Hurwitz, Herbert I., Uppal, Nikhil, Wagner, Stephanie A., Bendell, Johanna C., Beck, J. Thaddeus, Wade, Seaborn M., Nemunaitis, John J., Stella, Philip J., Pipas, J. Marc, Wainberg, Zev A., Manges, Robert, Garrett, William M., Hunter, Deborah S., Clark, Jason, Leopold, Lance, Sandor, Victor, Levy, Richard S.
Veröffentlicht in J Clin Oncol (2015)

Efficacy and Safety of Avelumab Treatment in Patients With Advanced Unresectable Mesothelioma: Phase 1b Results From the JAVELIN Solid Tumor Trial

von Hassan, Raffit, Thomas, Anish, Nemunaitis, John J., Patel, Manish R., Bennouna, Jaafar, Chen, Franklin L., Delord, Jean-Pierre, Dowlati, Afshin, Kochuparambil, Samith T., Taylor, Matthew H., Powderly, John D., Vaishampayan, Ulka N., Verschraegen, Claire, Grote, Hans Juergen, von Heydebreck, Anja, Chin, Kevin, Gulley, James L.
Veröffentlicht in JAMA Oncol (2019)

Survivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients

von Berinstein, Neil L, Karkada, Mohan, Oza, Amit M, Odunsi, Kunle, Villella, Jeannine A, Nemunaitis, John J, Morse, Michael A, Pejovic, Tanja, Bentley, James, Buyse, Marc, Nigam, Rita, Weir, Genevieve M, MacDonald, Lisa D, Quinton, Tara, Rajagopalan, Rajkannan, Sharp, Kendall, Penwell, Andrea, Sammatur, Leeladhar, Burzykowski, Tomasz, Stanford, Marianne M, Mansour, Marc
Veröffentlicht in Oncoimmunology (2015)

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

von Jamieson, Stephen M.F., Tsai, Peter, Kondratyev, Maria K., Budhani, Pratha, Liu, Arthur, Senzer, Neil N., Chiorean, E. Gabriela, Jalal, Shadia I., Nemunaitis, John J., Kee, Dennis, Shome, Avik, Wong, Way W., Li, Dan, Poonawala-Lohani, Nooriyah, Kakadia, Purvi M., Knowlton, Nicholas S., Lynch, Courtney R.H., Hong, Cho R., Lee, Tet Woo, Grénman, Reidar A., Caporiccio, Laura, McKee, Trevor D., Zaidi, Mark, Butt, Sehrish, Macann, Andrew M.J., McIvor, Nicholas P., Chaplin, John M., Hicks, Kevin O., Bohlander, Stefan K., Wouters, Bradly G., Hart, Charles P., Print, Cristin G., Wilson, William R., Curran, Michael A., Hunter, Francis W.
Veröffentlicht in JCI Insight (2018)