Systems approaches to design of targeted therapeutic delivery

Por Myerson, Jacob W., Brenner, Jacob S., Greineder, Colin F., Muzykantov, Vladimir R.
Publicado no Wiley Interdiscip Rev Syst Biol Med (2015)

Inhibition of Thrombin with PPACK-Nanoparticles Restores Disrupted Endothelial Barriers and Attenuates Thrombotic Risk in Experimental Atherosclerosis

Por Palekar, Rohun U., Jallouk, Andrew P., Myerson, Jacob W., Pan, Hua, Wickline, Samuel A.
Publicado no Arterioscler Thromb Vasc Biol (2016)

Non-affinity factors modulating vascular targeting of nano- and microcarriers

Por Myerson, Jacob W., Anselmo, Aaron C., Liu, Yaling, Mitragotri, Samir, Eckmann, David M., Muzykantov, Vladimir R.
Publicado no Adv Drug Deliv Rev (2015)

Thrombin-Targeted Liposomes Establish A Sustained Localized Anticlotting Barrier Against Acute Thrombosis

Por Palekar, Rohun U., Myerson, Jacob W., Schlesinger, Paul H., Sadler, J. Evan, Pan, Hua, Wickline, Samuel A.
Publicado em 2013

Unintended effects of drug carriers: big issues of small particles

Por Parhiz, Hamideh, Khoshnejad, Makan, Myerson, Jacob W., Hood, Elizabeth, Patel, Priyal N., Brenner, Jacob S., Muzykantov, Vladimir R.
Publicado no Adv Drug Deliv Rev (2018)

Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells

Por Pan, Daniel C., Myerson, Jacob W., Brenner, Jacob S., Patel, Priyal N., Anselmo, Aaron C., Mitragotri, Samir, Muzykantov, Vladimir
Publicado no Sci Rep (2018)

PPACK and Bivalirudin nanoparticles enable simultaneous imaging and potent inhibition of acute clotting

Por Myerson Jacob W, Allen John S, Williams Todd A, He Li, Tollefsen Douglas M, Lanza Gregory, Caruthers Shelton D, Wickline Samuel A
Publicado em 2012-02-01

PPACK and Bivalirudin nanoparticles enable simultaneous imaging and potent inhibition of acute clotting

Por Myerson, Jacob W, Allen, John S, Williams, Todd A, He, Li, Tollefsen, Douglas M, Lanza, Gregory, Caruthers, Shelton D, Wickline, Samuel A
Publicado em 2012

Lipid membrane editing with peptide cargo linkers in cells and synthetic nanostructures

Por Pan, Hua, Myerson, Jacob W., Ivashyna, Olena, Soman, Neelesh R., Marsh, Jon N., Hood, Joshua L., Lanza, Gregory M., Schlesinger, Paul H., Wickline, Samuel A.
Publicado em 2010

Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain

Por Marcos-Contreras, Oscar A, Brenner, Jacob S., Kiseleva, Raisa Y, Zuluaga-Ramirez, Viviana, Greineder, Colin F., Villa, Carlos H., Hood, Elizabeth D, Myerson, Jacob W, Muro, Silvia, Persidsky, Yuri, Muzykantov, Vladimir R.
Publicado no J Control Release (2019)

Quantifying progression and regression of thrombotic risk in experimental atherosclerosis

Por Palekar, Rohun U., Jallouk, Andrew P., Goette, Matthew J., Chen, Junjie, Myerson, Jacob W., Allen, John S., Akk, Antonina, Yang, Lihua, Tu, Yizheng, Miller, Mark J., Pham, Christine T. N., Wickline, Samuel A., Pan, Hua
Publicado no FASEB J (2015)

Programmable nanoparticle functionalization for in vivo targeting

Por Pan, Hua, Myerson, Jacob W., Hu, Lingzhi, Marsh, Jon N., Hou, Kirk, Scott, Michael J., Allen, John S., Hu, Grace, San Roman, Susana, Lanza, Gregory M., Schreiber, Robert D., Schlesinger, Paul H., Wickline, Samuel A.
Publicado em 2013

Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions

Por Brenner, Jacob S., Bhamidipati, Kartik, Glassman, Patrick M., Ramakrishnan, N., Jiang, Depeng, Paris, Andrew J., Myerson, Jacob W., Pan, Daniel C., Shuvaev, Vladimir V., Villa, Carlos H., Hood, Elizabeth D, Kiseleva, Raisa, Greineder, Colin F., Radhakrishnan, Ravi, Muzykantov, Vladimir R.
Publicado no Nanomedicine (2017)

Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles

Por Myerson, Jacob W, Braender, Bruce, Mcpherson, Olivia, Glassman, Patrick M, Kiseleva, Raisa Y, Shuvaev, Vladimir V, Marcos-Contreras, Oscar, Grady, Martha E, Lee, Hyun-Su, Greineder, Colin F, Stan, Radu V, Composto, Russell J, Eckmann, David M, Muzykantov, Vladimir R
Publicado no Adv Mater (2018)

Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function

Por Bibee, Kristin P., Cheng, Ya-Jian, Ching, James K., Marsh, Jon N., Li, Allison J., Keeling, Richard M., Connolly, Anne M., Golumbek, Paul T., Myerson, Jacob W., Hu, Grace, Chen, Junjie, Shannon, William D., Lanza, Gregory M., Weihl, Conrad C., Wickline, Samuel A.
Publicado em 2014

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude

Por Brenner, Jacob S., Pan, Daniel C., Myerson, Jacob W., Marcos-Contreras, Oscar A., Villa, Carlos H., Patel, Priyal, Hekierski, Hugh, Chatterjee, Shampa, Tao, Jian-Qin, Parhiz, Hamideh, Bhamidipati, Kartik, Uhler, Thomas G., Hood, Elizabeth D., Kiseleva, Raisa Yu., Shuvaev, Vladimir S., Shuvaeva, Tea, Khoshnejad, Makan, Johnston, Ian, Gregory, Jason V., Lahann, Joerg, Wang, Tao, Cantu, Edward, Armstead, William M., Mitragotri, Samir, Muzykantov, Vladimir
Publicado no Nat Commun (2018)