Thrombin-Targeted Liposomes Establish A Sustained Localized Anticlotting Barrier Against Acute Thrombosis

The goal of the present work was to design and test an acute-use nanoparticle-based antithrombotic agent that exhibits sustained local inhibition of thrombin without requiring a systemic anticoagulant effect to function against acute arterial thrombosis. To demonstrate proof of concept, we functiona...

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Detaylı Bibliyografya
Asıl Yazarlar: Palekar, Rohun U., Myerson, Jacob W., Schlesinger, Paul H., Sadler, J. Evan, Pan, Hua, Wickline, Samuel A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946534/
https://ncbi.nlm.nih.gov/pubmed/24063304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400210q
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