Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication

Por Holmes, J. Bradley, Akman, Gokhan, Wood, Stuart R., Sakhuja, Kiran, Cerritelli, Susana M., Moss, Chloe, Bowmaker, Mark R., Jacobs, Howard T., Crouch, Robert J., Holt, Ian J.
Publicado no Proc Natl Acad Sci U S A (2015)

Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria

Por Akman, Gokhan, Desai, Radha, Bailey, Laura J., Yasukawa, Takehiro, Dalla Rosa, Ilaria, Durigon, Romina, Holmes, J. Bradley, Moss, Chloe F., Mennuni, Mara, Houlden, Henry, Crouch, Robert J., Hanna, Michael G., Pitceathly, Robert D. S., Spinazzola, Antonella, Holt, Ian J.
Publicado no Proc Natl Acad Sci U S A (2016)

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

Por Moss, Chloe F., Dalla Rosa, Ilaria, Hunt, Lilian E., Yasukawa, Takehiro, Young, Robert, Jones, Aleck W. E., Reddy, Kaalak, Desai, Radha, Virtue, Sam, Elgar, Greg, Voshol, Peter, Taylor, Martin S., Holt, Ian J., Reijns, Martin A. M., Spinazzola, Antonella
Publicado no Nucleic Acids Res (2017)

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

Por Dalla Rosa, Ilaria, Cámara, Yolanda, Durigon, Romina, Moss, Chloe F., Vidoni, Sara, Akman, Gokhan, Hunt, Lilian, Johnson, Mark A., Grocott, Sarah, Wang, Liya, Thorburn, David R., Hirano, Michio, Poulton, Joanna, Taylor, Robert W., Elgar, Greg, Martí, Ramon, Voshol, Peter, Holt, Ian J., Spinazzola, Antonella
Publicado no PLoS Genet (2016)