Progress in Prediction and Interpretation of Clinically Relevant Metabolic Drug-Drug Interactions: a Minireview Illustrating Recent Developments and Current Opportunities

Por Fowler, Stephen, Morcos, Peter N., Cleary, Yumi, Martin-Facklam, Meret, Parrott, Neil, Gertz, Michael, Yu, Li
Publicado no Curr Pharmacol Rep (2017)

Pharmacokinetic/Pharmacodynamic Predictors of Clinical Potency for Hepatitis C Virus Nonnucleoside Polymerase and Protease Inhibitors

Por Reddy, Micaela B., Morcos, Peter N., Le Pogam, Sophie, Ou, Ying, Frank, Karl, Lave, Thierry, Smith, Patrick
Publicado em 2012

Pharmacokinetics and safety of oseltamivir in patients with end-stage renal disease treated with automated peritoneal dialysis

Por Patel, Kashyap, Rayner, Craig R, Giraudon, Mylène, Kamal, Mohamed A, Morcos, Peter N, Robson, Richard, Kirkpatrick, Carl M
Publicado no Br J Clin Pharmacol (2015)

Effect of a Modified Saquinavir/Ritonavir Dosing Regimen with Lower Dose Lead-In Phase on QTc Interval, Pharmacokinetics, Antiviral Activity and Safety in Treatment-Naïve HIV-1-Inf...

Por Boffito, Marta, Jackson, Akil, Pozniak, Anton, Giraudon, Mylene, Kulkarni, Rohit, Abelardo, Maria Connie, Patel, Indravadan H., Morcos, Peter N.
Publicado no Drugs R D (2015)

Metabolites of alectinib in human: their identification and pharmacological activity

Por Sato-Nakai, Mika, Kawashima, Kosuke, Nakagawa, Toshito, Tachibana, Yukako, Yoshida, Miyuki, Takanashi, Kenji, Morcos, Peter N., Binder, Martin, Moore, David J, Yu, Li
Publicado no Heliyon (2017)

Safety, Tolerability, and Pharmacokinetics of Intravenous Oseltamivir: Single- and Multiple-Dose Phase I Studies with Healthy Volunteers

Por Brennan, Barbara J., Davies, Brian, Cirrincione-Dall, Georgina, Morcos, Peter N., Beryozkina, Anna, Chappey, Colombe, Aceves Baldó, Pau, Lennon-Chrimes, Sian, Rayner, Craig R.
Publicado em 2012

Efficacy and Safety of Danoprevir-Ritonavir plus Peginterferon Alfa-2a–Ribavirin in Hepatitis C Virus Genotype 1 Prior Null Responders

Por Gane, Edward J., Rouzier, Régine, Wiercinska-Drapalo, Alicja, Larrey, Dominique G., Morcos, Peter N., Brennan, Barbara J., Le Pogam, Sophie, Nájera, Isabel, Petric, Rosemary, Tran, Jonathan Q., Kulkarni, Rohit, Zhang, Ying, Smith, Patrick, Yetzer, Ellen S., Shulman, Nancy S.
Publicado em 2014