Metabolites of alectinib in human: their identification and pharmacological activity

Por Sato-Nakai, Mika, Kawashima, Kosuke, Nakagawa, Toshito, Tachibana, Yukako, Yoshida, Miyuki, Takanashi, Kenji, Morcos, Peter N., Binder, Martin, Moore, David J, Yu, Li
Publicado no Heliyon (2017)

Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning

Por Aoki, Toshihiro, Hyohdoh, Ikumi, Furuichi, Noriyuki, Ozawa, Sawako, Watanabe, Fumio, Matsushita, Masayuki, Sakaitani, Masahiro, Morikami, Kenji, Takanashi, Kenji, Harada, Naoki, Tomii, Yasushi, Shiraki, Koji, Furumoto, Kentaro, Tabo, Mitsuyasu, Yoshinari, Kiyoshi, Ori, Kazutomo, Aoki, Yuko, Shimma, Nobuo, Iikura, Hitoshi
Publicado em 2014

Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties

Por Hyohdoh, Ikumi, Furuichi, Noriyuki, Aoki, Toshihiro, Itezono, Yoshiko, Shirai, Haruyoshi, Ozawa, Sawako, Watanabe, Fumio, Matsushita, Masayuki, Sakaitani, Masahiro, Ho, Pil-Su, Takanashi, Kenji, Harada, Naoki, Tomii, Yasushi, Yoshinari, Kiyoshi, Ori, Kazutomo, Tabo, Mitsuyasu, Aoki, Yuko, Shimma, Nobuo, Iikura, Hitoshi
Publicado em 2013