Pharmacokinetic/Pharmacodynamic Predictors of Clinical Potency for Hepatitis C Virus Nonnucleoside Polymerase and Protease Inhibitors

This analysis was conducted to determine whether the hepatitis C virus (HCV) viral kinetics (VK) model can predict viral load (VL) decreases for nonnucleoside polymerase inhibitors (NNPolIs) and protease inhibitors (PIs) after 3-day monotherapy studies of patients infected with genotype 1 chronic HC...

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Autors principals: Reddy, Micaela B., Morcos, Peter N., Le Pogam, Sophie, Ou, Ying, Frank, Karl, Lave, Thierry, Smith, Patrick
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370793/
https://ncbi.nlm.nih.gov/pubmed/22470110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06283-11
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