Workflow for High-content, Individual Cell Quantification of Fluorescent Markers from Universal Microscope Data, Supported by Open Source Software

Por Stockwell, Simon R., Mittnacht, Sibylle
Publicado no J Vis Exp (2014)

RB activation defect in tumor cell lines

Por Broceño, Cristina, Wilkie, Scott, Mittnacht, Sibylle
Publicado em 2002

RB in DNA repair

Por Huang, Paul H., Cook, Rebecca, Mittnacht, Sibylle
Publicado no Oncotarget (2015)

Latent Nuclear Antigen of Kaposi’s Sarcoma-Associated Herpesvirus Interacts with RING3, a Homolog of the Drosophila Female Sterile Homeotic (fsh) Gene

Por Platt, Georgina M., Simpson, Guy R., Mittnacht, Sibylle, Schulz, Thomas F.
Publicado em 1999

Cyclin-Cyclin-dependent Kinase Regulatory Response Is Linked to Substrate Recognition

Por Cuomo, Maria Emanuela, Platt, Georgina M., Pearl, Laurence H., Mittnacht, Sibylle
Publicado em 2011

Retinoblastoma family proteins: New players in DNA repair by non-homologous end-joining

Por Huang, Paul H., Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Mittnacht, Sibylle
Publicado no Mol Cell Oncol (2015)

Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb

Por Mittnacht Sibylle, Ludlow John W, Bianchi Mariarita, Vietri Michele, Villa-Moruzzi Emma
Publicado em 2006-02-01

Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb

Por Vietri, Michele, Bianchi, Mariarita, Ludlow, John W, Mittnacht, Sibylle, Villa-Moruzzi, Emma
Publicado em 2006

Structural Insights into the Mechanism of Phosphoregulation of the Retinoblastoma Protein

Por Lamber, Ekaterina P., Beuron, Fabienne, Morris, Edward P., Svergun, Dmitri I., Mittnacht, Sibylle
Publicado em 2013

Mechanism-Based Screen Establishes Signalling Framework for DNA Damage-Associated G1 Checkpoint Response

Por Richardson, Elizabeth, Stockwell, Simon R., Li, He, Aherne, Wynne, Cuomo, Maria Emanuela, Mittnacht, Sibylle
Publicado em 2012

Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

Por Oliver, Antony W, Paul, Angela, Boxall, Katherine J, Barrie, S Elaine, Aherne, G Wynne, Garrett, Michelle D, Mittnacht, Sibylle, Pearl, Laurence H
Publicado em 2006

Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture

Por Hassler, Markus, Singh, Shradha, Yu, Wyatt W., Luczynski, Maciej, Lakbir, Rachid, Sanchez-Sanchez, Francisco, Bader, Thomas, Pearl, Laurence H., Mittnacht, Sibylle
Publicado no Mol Cell (2007)

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

Por Xiao, Bing, Spencer, James, Clements, Adrienne, Ali-Khan, Nadeem, Mittnacht, Sibylle, Broceño, Cristina, Burghammer, Manfred, Perrakis, Anastassis, Marmorstein, Ronen, Gamblin, Steven J.
Publicado em 2003

Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining

Por Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Rieger, Simone, Moquet, Jayne, Spanswick, Victoria J., Hartley, John A., Rothkamm, Kai, Huang, Paul H., Mittnacht, Sibylle
Publicado no Cell Rep (2015)

Mechanism-Based Screen for G1/S Checkpoint Activators Identifies a Selective Activator of EIF2AK3/PERK Signalling

Por Stockwell, Simon R., Platt, Georgina, Barrie, S. Elaine, Zoumpoulidou, Georgia, te Poele, Robert H., Aherne, G. Wynne, Wilson, Stuart C., Sheldrake, Peter, McDonald, Edward, Venet, Mathilde, Soudy, Christelle, Elustondo, Frédéric, Rigoreau, Laurent, Blagg, Julian, Workman, Paul, Garrett, Michelle D., Mittnacht, Sibylle
Publicado em 2012