AAV-PHP.eB transduces both the inner and outer retina with high efficacy in mice

Por Arpad Palfi, Naomi Chadderton, Sophia Millington-Ward, Iris Post, Pete Humphries, Paul F. Kenna, G. Jane Farrar
Publicado em 2022-06-01

Clinical and molecular genetic characterisation of a family segregating autosomal dominant retinitis pigmentosa and sensorineural deafness

Por Kenna, P., Mansergh, F., Millington-Ward, S., Erven, A., Kumar-Singh, R., Brennan, R., Farrar, G, Humphries, P.
Publicado em 1997

Retinitis pigmentosa and progressive sensorineural hearing loss caused by a C12258A mutation in the mitochondrial MTTS2 gene.

Por Mansergh, F C, Millington-Ward, S, Kennan, A, Kiang, A S, Humphries, M, Farrar, G J, Humphries, P, Kenna, P F
Publicado em 1999

A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors

Por Hanlon, Killian S., Chadderton, Naomi, Palfi, Arpad, Blanco Fernandez, Alfonso, Humphries, Peter, Kenna, Paul F., Millington-Ward, Sophia, Farrar, G. Jane
Publicado no Front Neurosci (2017)

Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho(–/–) mouse

Por Palfi, Arpad, Chadderton, Naomi, O’Reilly, Mary, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul, Millington-Ward, Sophia, Farrar, Jane
Publicado no Mol Ther Methods Clin Dev (2015)

Corrigendum to “Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho–/– mouse”

Por Palfi, Arpad, Chadderton, Naomi, O’Reilly, Mary, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul, Millington-Ward, Sophia, Farrar, Jane
Publicado no Mol Ther Methods Clin Dev (2016)

The X chromosome shows less genetic variation at restriction sites than the autosomes.

Por Hofker, M H, Skraastad, M I, Bergen, A A, Wapenaar, M C, Bakker, E, Millington-Ward, A, van Ommen, G J, Pearson, P L
Publicado em 1986

Toward an elucidation of the molecular genetics of inherited retinal degenerations

Por Farrar, G. Jane, Carrigan, Matthew, Dockery, Adrian, Millington-Ward, Sophia, Palfi, Arpad, Chadderton, Naomi, Humphries, Marian, Kiang, Anna Sophia, Kenna, Paul F., Humphries, Pete
Publicado no Hum Mol Genet (2017)

Improved Retinal Function in a Mouse Model of Dominant Retinitis Pigmentosa Following AAV-delivered Gene Therapy

Por Chadderton, Naomi, Millington-Ward, Sophia, Palfi, Arpad, O'Reilly, Mary, Tuohy, Gearóid, Humphries, Marian M, Li, Tiansen, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2009

microRNA regulatory circuits in a mouse model of inherited retinal degeneration

Por Palfi, Arpad, Hokamp, Karsten, Hauck, Stefanie M., Vencken, Sebastian, Millington-Ward, Sophia, Chadderton, Naomi, Carrigan, Mathew, Kortvely, Elod, Greene, Catherine M., Kenna, Paul F., Farrar, G. Jane
Publicado no Sci Rep (2016)

Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

Por Millington-Ward, Sophia, Chadderton, Naomi, O'Reilly, Mary, Palfi, Arpad, Goldmann, Tobias, Kilty, Claire, Humphries, Marian, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2011

Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy

Por Chadderton, Naomi, Palfi, Arpad, Millington-Ward, Sophia, Gobbo, Oliverio, Overlack, Nora, Carrigan, Matthew, O'Reilly, Mary, Campbell, Matthew, Ehrhardt, Carsten, Wolfrum, Uwe, Humphries, Peter, Kenna, Paul F, Jane Farrar, G
Publicado em 2013

RNA Interference–Mediated Suppression and Replacement of Human Rhodopsin In Vivo

Por O’Reilly, Mary , Palfi, Arpad , Chadderton, Naomi , Millington-Ward, Sophia , Ader, Marius , Cronin, Thérèse , Tuohy, Thérèse , Auricchio, Alberto , Hildinger, Markus , Tivnan, Amanda , McNally, Niamh , Humphries, Marian M. , Kiang, Anna-Sophia , Humphries, Pete , Kenna, Paul F. , Farrar, G. Jane 
Publicado em 2007

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence C S, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence CS, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011