NEW EMBO MEMBER’S REVIEW: On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

Por Farrar, G.Jane, Kenna, Paul F., Humphries, Peter
Publicado em 2002

Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy

Por Mansergh, Fiona C, Chadderton, Naomi, Kenna, Paul F, Gobbo, Oliviero L, Farrar, G Jane
Publicado em 2014

A novel homozygous truncating GNAT1 mutation implicated in retinal degeneration

Por Carrigan, Matthew, Duignan, Emma, Humphries, Pete, Palfi, Arpad, Kenna, Paul F, Farrar, G Jane
Publicado no Br J Ophthalmol (2016)

Hedgehog Signaling Pathway Database: a repository of current annotation efforts and resources for the Hh research community

Por Hervold, Kieran, Martin, Andrew, Kirkpatrick, Roger A., Mc Kenna, Paul F., Ramirez-Weber, F. A.
Publicado em 2007

Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

Por Loscher, Carol J, Hokamp, Karsten, Kenna, Paul F, Ivens, Alasdair C, Humphries, Peter, Palfi, Arpad, Farrar, G Jane
Publicado em 2007

ON THE ROLE OF IMPDH1 IN RETINAL DEGENERATION

Por Kennan, Avril, Aherne, Aileen, Bowne, Sara J., Daiger, Stephen P., Jane Farrar, G., Kenna, Paul F., Humphries, Pete
Publicado em 2003

A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors

Por Hanlon, Killian S., Chadderton, Naomi, Palfi, Arpad, Blanco Fernandez, Alfonso, Humphries, Peter, Kenna, Paul F., Millington-Ward, Sophia, Farrar, G. Jane
Publicado no Front Neurosci (2017)

Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)

Por Tam, Lawrence C.S., Kiang, Anna-Sophia, Campbell, Matthew, Keaney, James, Jane Farrar, G., Humphries, Marian M., Kenna, Paul F., Humphries, Pete
Publicado em 2010

C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa

Por Humphries, Marian M, Kenna, Paul F, Campbell, Matthew, Tam, Lawrence C S, Nguyen, Anh T H, Farrar, G Jane, Botto, Marina, Kiang, Anna Sophia, Humphries, Peter
Publicado em 2012

Improved Retinal Function in a Mouse Model of Dominant Retinitis Pigmentosa Following AAV-delivered Gene Therapy

Por Chadderton, Naomi, Millington-Ward, Sophia, Palfi, Arpad, O'Reilly, Mary, Tuohy, Gearóid, Humphries, Marian M, Li, Tiansen, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2009

microRNA regulatory circuits in a mouse model of inherited retinal degeneration

Por Palfi, Arpad, Hokamp, Karsten, Hauck, Stefanie M., Vencken, Sebastian, Millington-Ward, Sophia, Chadderton, Naomi, Carrigan, Mathew, Kortvely, Elod, Greene, Catherine M., Kenna, Paul F., Farrar, G. Jane
Publicado no Sci Rep (2016)

Panel-Based Population Next-Generation Sequencing for Inherited Retinal Degenerations

Por Carrigan, Matthew, Duignan, Emma, Malone, Conor P. G., Stephenson, Kirk, Saad, Tahira, McDermott, Ciara, Green, Andrew, Keegan, David, Humphries, Peter, Kenna, Paul F., Farrar, G. Jane
Publicado no Sci Rep (2016)

Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

Por Millington-Ward, Sophia, Chadderton, Naomi, O'Reilly, Mary, Palfi, Arpad, Goldmann, Tobias, Kilty, Claire, Humphries, Marian, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2011

An experimental platform for systemic drug delivery to the retina

Por Campbell, Matthew, Nguyen, Anh T. H., Kiang, Anna-Sophia, Tam, Lawrence C. S., Gobbo, Oliviero L., Kerskens, Christian, Dhubhghaill, Sorcha Ni, Humphries, Marian M., Farrar, G.-Jane, Kenna, Paul F., Humphries, Peter
Publicado em 2009

Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy

Por Chadderton, Naomi, Palfi, Arpad, Millington-Ward, Sophia, Gobbo, Oliverio, Overlack, Nora, Carrigan, Matthew, O'Reilly, Mary, Campbell, Matthew, Ehrhardt, Carsten, Wolfrum, Uwe, Humphries, Peter, Kenna, Paul F, Jane Farrar, G
Publicado em 2013

Systemic low-molecular weight drug delivery to pre-selected neuronal regions

Por Campbell, Matthew, Humphries, Marian M, Kiang, Anna-Sophia, Nguyen, Anh T H, Gobbo, Oliviero L, Tam, Lawrence C S, Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G-Jane, Kenna, Paul F, Humphries, Peter
Publicado em 2011

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

Por Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O’Neill, Luke A J, Hollyfield, Joe G, Humphries, Peter
Publicado em 2012

RNA Interference–Mediated Suppression and Replacement of Human Rhodopsin In Vivo

Por O’Reilly, Mary , Palfi, Arpad , Chadderton, Naomi , Millington-Ward, Sophia , Ader, Marius , Cronin, Thérèse , Tuohy, Thérèse , Auricchio, Alberto , Hildinger, Markus , Tivnan, Amanda , McNally, Niamh , Humphries, Marian M. , Kiang, Anna-Sophia , Humphries, Pete , Kenna, Paul F. , Farrar, G. Jane 
Publicado em 2007

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence C S, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence CS, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011