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Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)

Retinitis pigmentosa (RP) is the most prevalent cause of registered visual handicap among working aged populations of developed countries. Up to 40% of autosomal dominant cases of disease are caused by mutations within the rhodopsin, RDS-peripherin and inosine 5′-monophosphate dehydrogenase type 1 (...

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Detalhes bibliográficos
Main Authors: Tam, Lawrence C.S., Kiang, Anna-Sophia, Campbell, Matthew, Keaney, James, Jane Farrar, G., Humphries, Marian M., Kenna, Paul F., Humphries, Pete
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957325/
https://ncbi.nlm.nih.gov/pubmed/20817636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq369
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