NEW EMBO MEMBER’S REVIEW: On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

Por Farrar, G.Jane, Kenna, Paul F., Humphries, Peter
Publicado em 2002

Gene expression changes during retinal development and rod specification

Por Mansergh, Fiona C., Carrigan, Matthew, Hokamp, Karsten, Farrar, G. Jane
Publicado no Mol Vis (2015)

Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells

Por Geoghegan, Fintan, Chadderton, Naomi, Farrar, G. Jane, Zisterer, Daniela M., Porter, Richard K.
Publicado no Oncol Lett (2017)

Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy

Por Mansergh, Fiona C, Chadderton, Naomi, Kenna, Paul F, Gobbo, Oliviero L, Farrar, G Jane
Publicado em 2014

A novel homozygous truncating GNAT1 mutation implicated in retinal degeneration

Por Carrigan, Matthew, Duignan, Emma, Humphries, Pete, Palfi, Arpad, Kenna, Paul F, Farrar, G Jane
Publicado no Br J Ophthalmol (2016)

Common microRNA signature in mouse models of retinal degeneration

Por Loscher, Carol, Hokamp, Karsten, Wilson, John H., Li, Tiansen, Humphries, Peter, Farrar, G. Jane, Palfi, Arpad
Publicado em 2008

Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

Por Loscher, Carol J, Hokamp, Karsten, Kenna, Paul F, Ivens, Alasdair C, Humphries, Peter, Palfi, Arpad, Farrar, G Jane
Publicado em 2007

A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors

Por Hanlon, Killian S., Chadderton, Naomi, Palfi, Arpad, Blanco Fernandez, Alfonso, Humphries, Peter, Kenna, Paul F., Millington-Ward, Sophia, Farrar, G. Jane
Publicado no Front Neurosci (2017)

Target 5000: Target Capture Sequencing for Inherited Retinal Degenerations

Por Dockery, Adrian, Stephenson, Kirk, Keegan, David, Wynne, Niamh, Silvestri, Giuliana, Humphries, Peter, Kenna, Paul F., Carrigan, Matthew, Farrar, G. Jane
Publicado no Genes (Basel) (2017)

C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa

Por Humphries, Marian M, Kenna, Paul F, Campbell, Matthew, Tam, Lawrence C S, Nguyen, Anh T H, Farrar, G Jane, Botto, Marina, Kiang, Anna Sophia, Humphries, Peter
Publicado em 2012

Improved Retinal Function in a Mouse Model of Dominant Retinitis Pigmentosa Following AAV-delivered Gene Therapy

Por Chadderton, Naomi, Millington-Ward, Sophia, Palfi, Arpad, O'Reilly, Mary, Tuohy, Gearóid, Humphries, Marian M, Li, Tiansen, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2009

microRNA regulatory circuits in a mouse model of inherited retinal degeneration

Por Palfi, Arpad, Hokamp, Karsten, Hauck, Stefanie M., Vencken, Sebastian, Millington-Ward, Sophia, Chadderton, Naomi, Carrigan, Mathew, Kortvely, Elod, Greene, Catherine M., Kenna, Paul F., Farrar, G. Jane
Publicado no Sci Rep (2016)

Panel-Based Population Next-Generation Sequencing for Inherited Retinal Degenerations

Por Carrigan, Matthew, Duignan, Emma, Malone, Conor P. G., Stephenson, Kirk, Saad, Tahira, McDermott, Ciara, Green, Andrew, Keegan, David, Humphries, Peter, Kenna, Paul F., Farrar, G. Jane
Publicado no Sci Rep (2016)

Recombination between rhodopsin and locus D3S47 (C17) in rhodopsin retinitis pigmentosa families

Por Inglehearn, Chris F., Lester, Douglas H., Bashir, Rumaisa, Atif, Uzma, Keen, T. Jeffrey, Sertedaki, Amalia, Lindsey, Janet, Jay, Marcelle, Bird, Alan C., Farrar, G. Jane, Humphries, Peter, Bhattacharya, Shomi S.
Publicado em 1992

Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

Por Millington-Ward, Sophia, Chadderton, Naomi, O'Reilly, Mary, Palfi, Arpad, Goldmann, Tobias, Kilty, Claire, Humphries, Marian, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado em 2011

An experimental platform for systemic drug delivery to the retina

Por Campbell, Matthew, Nguyen, Anh T. H., Kiang, Anna-Sophia, Tam, Lawrence C. S., Gobbo, Oliviero L., Kerskens, Christian, Dhubhghaill, Sorcha Ni, Humphries, Marian M., Farrar, G.-Jane, Kenna, Paul F., Humphries, Peter
Publicado em 2009

Systemic low-molecular weight drug delivery to pre-selected neuronal regions

Por Campbell, Matthew, Humphries, Marian M, Kiang, Anna-Sophia, Nguyen, Anh T H, Gobbo, Oliviero L, Tam, Lawrence C S, Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G-Jane, Kenna, Paul F, Humphries, Peter
Publicado em 2011

RNA Interference–Mediated Suppression and Replacement of Human Rhodopsin In Vivo

Por O’Reilly, Mary , Palfi, Arpad , Chadderton, Naomi , Millington-Ward, Sophia , Ader, Marius , Cronin, Thérèse , Tuohy, Thérèse , Auricchio, Alberto , Hildinger, Markus , Tivnan, Amanda , McNally, Niamh , Humphries, Marian M. , Kiang, Anna-Sophia , Humphries, Pete , Kenna, Paul F. , Farrar, G. Jane 
Publicado em 2007

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence C S, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement

Por Bowne, Sara J, Humphries, Marian M, Sullivan, Lori S, Kenna, Paul F, Tam, Lawrence CS, Kiang, Anna S, Campbell, Matthew, Weinstock, George M, Koboldt, Daniel C, Ding, Li, Fulton, Robert S, Sodergren, Erica J, Allman, Denis, Millington-Ward, Sophia, Palfi, Arpad, McKee, Alex, Blanton, Susan H, Slifer, Susan, Konidari, Ioanna, Farrar, G Jane, Daiger, Stephen P, Humphries, Peter
Publicado em 2011