Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells

Phenformin, a member of the biguanides class of drugs, has been reported to be efficacious in cancer treatment. The focus of the current study was to establish whether there were direct effects of phenformin on the metabolism and bioenergetics of neuroblastoma SH-SY5Y cancer cells. Cell viability wa...

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Published in:Oncol Lett
Main Authors: Geoghegan, Fintan, Chadderton, Naomi, Farrar, G. Jane, Zisterer, Daniela M., Porter, Richard K.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661415/
https://ncbi.nlm.nih.gov/pubmed/29113281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6929
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