The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors

Por Schmitt, Emmanuelle, Blanquet, Sylvain, Mechulam, Yves
Publicado em 2002

Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

Por Yatime, Laure, Mechulam, Yves, Blanquet, Sylvain, Schmitt, Emmanuelle
Publicado em 2007

A unique conformation of the anticodon stem-loop is associated with the capacity of tRNA(f)(Met) to initiate protein synthesis

Por Barraud, Pierre, Schmitt, Emmanuelle, Mechulam, Yves, Dardel, Frédéric, Tisné, Carine
Publicado em 2008

Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2

Por Dubiez, Etienne, Aleksandrov, Alexey, Lazennec-Schurdevin, Christine, Mechulam, Yves, Schmitt, Emmanuelle
Publicado no Nucleic Acids Res (2015)

Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core

Por Schmitt, Emmanuelle, Coureux, Pierre-Damien, Monestier, Auriane, Dubiez, Etienne, Mechulam, Yves
Publicado no Int J Mol Sci (2019)

Role of aIF1 in Pyrococcus abyssi translation initiation

Por Monestier, Auriane, Lazennec-Schurdevin, Christine, Coureux, Pierre-Damien, Mechulam, Yves, Schmitt, Emmanuelle
Publicado no Nucleic Acids Res (2018)

Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

Por Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Bourcier, Sophie, Mechulam, Yves, Schmitt, Emmanuelle
Publicado no Commun Biol (2020)

Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power

Por Opuu, Vaitea, Nigro, Giuliano, Gaillard, Thomas, Schmitt, Emmanuelle, Mechulam, Yves, Simonson, Thomas
Publicado no PLoS Comput Biol (2020)

Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates

Por Bourgeois, Gabrielle, Seguin, Jérôme, Babin, Morgan, Gondry, Muriel, Mechulam, Yves, Schmitt, Emmanuelle
Publicado no RNA (2020)

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

Por Tanrikulu, I. Caglar, Schmitt, Emmanuelle, Mechulam, Yves, Goddard, William A., Tirrell, David A.
Publicado em 2009

Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA

Por Naveau, Marie, Lazennec-Schurdevin, Christine, Panvert, Michel, Dubiez, Etienne, Mechulam, Yves, Schmitt, Emmanuelle
Publicado em 2013

The structure of an E. coli tRNA(f)(Met) A(1)–U(72) variant shows an unusual conformation of the A(1)–U(72) base pair

Por Monestier, Auriane, Aleksandrov, Alexey, Coureux, Pierre-Damien, Panvert, Michel, Mechulam, Yves, Schmitt, Emmanuelle
Publicado no RNA (2017)

Intrinsic resistance to aminoglycosides in Enterococcus faecium is conferred by the 16S rRNA m(5)C1404-specific methyltransferase EfmM

Por Galimand, Marc, Schmitt, Emmanuelle, Panvert, Michel, Desmolaize, Benoît, Douthwaite, Stephen, Mechulam, Yves, Courvalin, Patrice
Publicado em 2011

Recent Advances in Archaeal Translation Initiation

Por Schmitt, Emmanuelle, Coureux, Pierre-Damien, Kazan, Ramy, Bourgeois, Gabrielle, Lazennec-Schurdevin, Christine, Mechulam, Yves
Publicado no Front Microbiol (2020)

Switching from an induced fit to a lock and key mechanism in an aminoacyl-tRNA synthetase with modified specificity

Por Schmitt, Emmanuelle, Tanrikulu, I. Caglar, Yoo, Tae Hyeon, Panvert, Michel, Tirrell, David A., Mechulam, Yves
Publicado em 2009

Structure of a left-handed DNA G-quadruplex

Por Chung, Wan Jun, Heddi, Brahim, Schmitt, Emmanuelle, Lim, Kah Wai, Mechulam, Yves, Phan, Anh Tuân
Publicado no Proc Natl Acad Sci U S A (2015)

NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes

Por Winnerdy, Fernaldo Richtia, Bakalar, Blaž, Maity, Arijit, Vandana, J Jeya, Mechulam, Yves, Schmitt, Emmanuelle, Phan, Anh Tuân
Publicado no Nucleic Acids Res (2019)

Cryo-EM study of start codon selection during archaeal translation initiation

Por Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Monestier, Auriane, Larquet, Eric, Cladière, Lionel, Klaholz, Bruno P., Schmitt, Emmanuelle, Mechulam, Yves
Publicado no Nat Commun (2016)

Bulges in left-handed G-quadruplexes

Por Das, Poulomi, Ngo, Khac Huy, Winnerdy, Fernaldo Richtia, Maity, Arijit, Bakalar, Blaž, Mechulam, Yves, Schmitt, Emmanuelle, Phan, Anh Tuân
Publicado no Nucleic Acids Res (2021)

Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells

Por Fedry, Juliette, Silva, Joana, Vanevic, Mihajlo, Fronik, Stanley, Mechulam, Yves, Schmitt, Emmanuelle, des Georges, Amédée, Faller, William James, Förster, Friedrich
Publicado no Mol Cell (2024)