Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

Archaeal translation initiation occurs within a macromolecular complex containing the small ribosomal subunit (30S) bound to mRNA, initiation factors aIF1, aIF1A and the ternary complex aIF2:GDPNP:Met-tRNA(i)(Met). Here, we determine the cryo-EM structure of a 30S:mRNA:aIF1A:aIF2:GTP:Met-tRNA(i)(Met...

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Publicado en:Commun Biol
Autores principales: Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Bourcier, Sophie, Mechulam, Yves, Schmitt, Emmanuelle
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005279/
https://ncbi.nlm.nih.gov/pubmed/32029867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0780-0
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