Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation

Archaeal translation initiation occurs within a macromolecular complex containing the small ribosomal subunit (30S) bound to mRNA, initiation factors aIF1, aIF1A and the ternary complex aIF2:GDPNP:Met-tRNA(i)(Met). Here, we determine the cryo-EM structure of a 30S:mRNA:aIF1A:aIF2:GTP:Met-tRNA(i)(Met...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Commun Biol
Prif Awduron: Coureux, Pierre-Damien, Lazennec-Schurdevin, Christine, Bourcier, Sophie, Mechulam, Yves, Schmitt, Emmanuelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005279/
https://ncbi.nlm.nih.gov/pubmed/32029867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0780-0
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