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Structure of a left-handed DNA G-quadruplex

Aside from the well-known double helix, DNA can also adopt an alternative four-stranded structure known as G-quadruplex. Implications of such a structure in cellular processes, as well as its therapeutic and diagnostic applications, have been reported. The G-quadruplex structure is highly polymorphi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chung, Wan Jun, Heddi, Brahim, Schmitt, Emmanuelle, Lim, Kah Wai, Mechulam, Yves, Phan, Anh Tuân
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352798/
https://ncbi.nlm.nih.gov/pubmed/25695967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418718112
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