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Structure of the human telomere in Na(+) solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity

Single-stranded DNA overhangs at the ends of human telomeric repeats are capable of adopting four-stranded G-quadruplex structures, which could serve as potential anticancer targets. Out of the five reported intramolecular human telomeric G-quadruplex structures, four were formed in the presence of...

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Detalhes bibliográficos
Main Authors: Lim, Kah Wai, Ng, Veronica Chinn Min, Martín-Pintado, Nerea, Heddi, Brahim, Phan, Anh Tuân
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905899/
https://ncbi.nlm.nih.gov/pubmed/23999095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt771
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