The allergy gene: how a mutation in a skin protein revealed a link between eczema and asthma

di McLean, W. H. Irwin
Pubblicazione 2011

One remarkable molecule: Filaggrin

di Brown, Sara J., McLean, W. H. Irwin
Pubblicazione 2011

Old King Coal — molecular mechanisms underlying an ancient treatment for atopic eczema

di McLean, W.H. Irwin, Irvine, Alan D.
Pubblicazione 2013

Keratin 6b variant p.Gly499Ser reported in delayed‐onset pachyonychia congenita is a non‐pathogenic polymorphism

di Smith, Frances J. D., McLean, W. H. Irwin
Pubblicato in J Dermatol (2017)

Filaggrin in the frontline: role in skin barrier function and disease

di Sandilands, Aileen, Sutherland, Calum, Irvine, Alan D., McLean, W. H. Irwin
Pubblicazione 2009

Identification of a Novel Family of Laminin N-terminal Alternate Splice Isoforms: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION

di Hamill, Kevin J., Langbein, Lutz, Jones, Jonathan C. R., McLean, W. H. Irwin
Pubblicazione 2009

Obtaining DNA in the mail from a national sample of children with a chronic non-fatal illness

di Margolis, David J., Papadopoulos, Maryte, Apter, Andrea, McLean, W. H. Irwin, Mitra, Nandita, Rebbeck, Tim
Pubblicazione 2011

A Lack of Premature Termination Codon Read-Through Efficacy of PTC124 (Ataluren) in a Diverse Array of Reporter Assays

di McElroy, Stuart P., Nomura, Toshifumi, Torrie, Leah S., Warbrick, Emma, Gartner, Ulrike, Wood, Gavin, McLean, W. H. Irwin
Pubblicazione 2013

Development of a Corneal Bioluminescence Mouse for Real-Time In Vivo Evaluation of Gene Therapies

di Fu, Dun Jack, Allen, Edwin H. A., Hickerson, Robyn P., Leslie Pedrioli, Deena M., McLean, W. H. Irwin
Pubblicato in Transl Vis Sci Technol (2020)

Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations

di O'Regan, Gráinne M., Campbell, Linda E., Cordell, Heather J., Irvine, Alan D., McLean, W.H. Irwin, Brown, Sara J.
Pubblicazione 2010

Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

di Kelleher, Maeve, Dunn-Galvin, Audrey, Hourihane, Jonathan O'B., Murray, Deirdre, Campbell, Linda E., McLean, W.H. Irwin, Irvine, Alan D.
Pubblicato in J Allergy Clin Immunol (2015)

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

di Hegde, Vikas, Hickerson, Robyn P., Nainamalai, Sitheswaran, Campbell, Paul A., Smith, Frances J.D., McLean, W.H. Irwin, Leslie Pedrioli, Deena M.
Pubblicato in J Control Release (2014)

Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants

di Flohr, Carsten, Perkin, Michael, Logan, Kirsty, Marrs, Tom, Radulovic, Suzana, Campbell, Linda E., MacCallum, Stephanie F., McLean, W.H. Irwin, Lack, Gideon
Pubblicazione 2013

Intragenic Copy Number Variation within Filaggrin Contributes to the Risk of Atopic Dermatitis with a Dose-Dependent Effect

di Brown, Sara J, Kroboth, Karin, Sandilands, Aileen, Campbell, Linda E, Pohler, Elizabeth, Kezic, Sanja, Cordell, Heather J, McLean, W H Irwin, Irvine, Alan D
Pubblicazione 2012

Carrier Status for the Common R501X and 2282del4 Filaggrin Mutations Is Not Associated with Hearing Phenotypes in 5377 Children from the ALSPAC Cohort

di Rodriguez, Santiago, Hall, Amanda J., Granell, Raquel, McLean, W. H. Irwin, Irvine, Alan D., Palmer, Colin N. A., Smith, George Davey, Henderson, John, Day, Ian N. M.
Pubblicazione 2009

Improved Annotation of 3′ Untranslated Regions and Complex Loci by Combination of Strand-Specific Direct RNA Sequencing, RNA-Seq and ESTs

di Schurch, Nicholas J., Cole, Christian, Sherstnev, Alexander, Song, Junfang, Duc, Céline, Storey, Kate G., McLean, W. H. Irwin, Brown, Sara J., Simpson, Gordon G., Barton, Geoffrey J.
Pubblicazione 2014

Allele-specific siRNA silencing for the common Keratin 12 founder mutation in Meesmann epithelial corneal dystrophy

di Allen, Edwin H. A., Atkinson, Sarah D., Liao, Haihui, Moore, Jonathan E., Pedrioli, Deena M. Leslie, Smith, Frances J. D., McLean, W. H. Irwin, Moore, C. B. Tara
Pubblicazione 2013

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

di Simpson, Eric L., Chalmers, Joanne R., Hanifin, Jon M., Thomas, Kim S., Cork, Michael J., McLean, W.H. Irwin, Brown, Sara J., Chen, Zunqiu, Chen, Yiyi, Williams, Hywel C.
Pubblicazione 2014

Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study

di Visser, Maaike J, Verberk, Maarten M, Campbell, Linda E, McLean, W H Irwin, Calkoen, Florentine, Bakker, Jan G, van Dijk, Frank J H, Bos, Jan D, Kezic, Sanja
Pubblicato in Contact Dermatitis (2014)

Filaggrin genotype does not determine the skin's threshold to UV-induced erythema

di Forbes, Deborah, Johnston, Leona, Gardner, June, MacCallum, Stephanie F., Campbell, Linda E., Dinkova-Kostova, Albena T., McLean, W.H. Irwin, Ibbotson, Sally H., Dawe, Robert S., Brown, Sara J.
Pubblicato in J Allergy Clin Immunol (2016)