Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations

Por O'Regan, Gráinne M., Campbell, Linda E., Cordell, Heather J., Irvine, Alan D., McLean, W.H. Irwin, Brown, Sara J.
Publicado em 2010

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

Por Cole, Christian, Kroboth, Karin, Schurch, Nicholas J., Sandilands, Aileen, Sherstnev, Alexander, O'Regan, Grainne M., Watson, Rosemarie M., Irwin McLean, W.H., Barton, Geoffrey J., Irvine, Alan D., Brown, Sara J.
Publicado em 2014

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin()

Por Thawer-Esmail, Fatemah, Jakasa, Ivone, Todd, Gail, Wen, Yaran, Brown, Sara J., Kroboth, Karin, Campbell, Linda E., O'Regan, Grainne M., McLean, W.H. Irwin, Irvine, Alan D., Kezic, Sanja, Sandilands, Aileen
Publicado em 2014

Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes

Por O'Regan, Gráinne M., Kemperman, Patrick M.J.H., Sandilands, Aileen, Chen, Huijia, Campbell, Linda E., Kroboth, Karin, Watson, Rosemarie, Rowland, Marion, Puppels, Gerwin J., McLean, W.H. Irwin, Caspers, Peter J., Irvine, Alan D.
Publicado em 2010

Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of fi...

Por Kezic, Sanja, O’Regan, Gráinne M., Lutter, René, Jakasa, Ivone, Koster, Ellen S., Saunders, Sean, Caspers, Peter, Kemperman, Patrick M.J.H., Puppels, Gerwin J., Sandilands, Aileen, Chen, Huijia, Campbell, Linda E., Kroboth, Karin, Watson, Rosemarie, Fallon, Padraic G., McLean, W. H. Irwin, Irvine, Alan D.
Publicado em 2012

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

Por Weidinger, Stephan, Willis-Owen, Saffron A.G., Kamatani, Yoichiro, Baurecht, Hansjörg, Morar, Nilesh, Liang, Liming, Edser, Pauline, Street, Teresa, Rodriguez, Elke, O'Regan, Grainne M., Beattie, Paula, Fölster-Holst, Regina, Franke, Andre, Novak, Natalija, Fahy, Caoimhe M., Winge, Mårten C.G., Kabesch, Michael, Illig, Thomas, Heath, Simon, Söderhäll, Cilla, Melén, Erik, Pershagen, Göran, Kere, Juha, Bradley, Maria, Lieden, Agne, Nordenskjold, Magnus, Harper, John I., Mclean, W.H. Irwin, Brown, Sara J., Cookson, William O.C., Lathrop, G. Mark, Irvine, Alan D., Moffatt, Miriam F.
Publicado em 2013

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

Por Baurecht, Hansjörg, Hotze, Melanie, Brand, Stephan, Büning, Carsten, Cormican, Paul, Corvin, Aiden, Ellinghaus, David, Ellinghaus, Eva, Esparza-Gordillo, Jorge, Fölster-Holst, Regina, Franke, Andre, Gieger, Christian, Hubner, Norbert, Illig, Thomas, Irvine, Alan D., Kabesch, Michael, Lee, Young A.E., Lieb, Wolfgang, Marenholz, Ingo, McLean, W.H. Irwin, Morris, Derek W., Mrowietz, Ulrich, Nair, Rajan, Nöthen, Markus M., Novak, Natalija, O’Regan, Grainne M., Schreiber, Stefan, Smith, Catherine, Strauch, Konstantin, Stuart, Philip E., Trembath, Richard, Tsoi, Lam C., Weichenthal, Michael, Barker, Jonathan, Elder, James T., Weidinger, Stephan, Cordell, Heather J., Brown, Sara J.
Publicado no Am J Hum Genet (2015)

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

Por Baurecht, Hansjörg, Hotze, Melanie, Brand, Stephan, Büning, Carsten, Cormican, Paul, Corvin, Aiden, Ellinghaus, David, Ellinghaus, Eva, Esparza-Gordillo, Jorge, Fölster-Holst, Regina, Franke, Andre, Gieger, Christian, Hubner, Norbert, Illig, Thomas, Irvine, Alan D., Kabesch, Michael, Lee, Young A.E., Lieb, Wolfgang, Marenholz, Ingo, McLean, W.H. Irwin, Morris, Derek W., Mrowietz, Ulrich, Nair, Rajan, Nöthen, Markus M., Novak, Natalija, O’Regan, Grainne M., Schreiber, Stefan, Smith, Catherine, Strauch, Konstantin, Stuart, Philip E., Trembath, Richard, Tsoi, Lam C., Weichenthal, Michael, Barker, Jonathan, Elder, James T., Weidinger, Stephan, Cordell, Heather J., Brown, Sara J.
Publicado no Am J Hum Genet (2015)

Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations

Por Mercier, Sandra, Küry, Sébastien, Salort-Campana, Emmanuelle, Magot, Armelle, Agbim, Uchenna, Besnard, Thomas, Bodak, Nathalie, Bou-Hanna, Chantal, Bréhéret, Flora, Brunelle, Perrine, Caillon, Florence, Chabrol, Brigitte, Cormier-Daire, Valérie, David, Albert, Eymard, Bruno, Faivre, Laurence, Figarella-Branger, Dominique, Fleurence, Emmanuelle, Ganapathi, Mythily, Gherardi, Romain, Goldenberg, Alice, Hamel, Antoine, Igual, Jeanine, Irvine, Alan D., Israël-Biet, Dominique, Kannengiesser, Caroline, Laboisse, Christian, Le Caignec, Cédric, Mahé, Jean-Yves, Mallet, Stéphanie, MacGowan, Stuart, McAleer, Maeve A., McLean, Irwin, Méni, Cécile, Munnich, Arnold, Mussini, Jean-Marie, Nagy, Peter L., Odel, Jeffrey, O’Regan, Grainne M., Péréon, Yann, Perrier, Julie, Piard, Juliette, Puzenat, Eve, Sampson, Jacinda B., Smith, Frances, Soufir, Nadem, Tanji, Kurenai, Thauvin, Christel, Ulane, Christina, Watson, Rosemarie M., Khumalo, Nonhlanhla P., Mayosi, Bongani M., Barbarot, Sébastien, Bézieau, Stéphane
Publicado no Orphanet J Rare Dis (2015)

Multi-ethnic genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Por Paternoster, Lavinia, Standl, Marie, Waage, Johannes, Baurecht, Hansjörg, Hotze, Melanie, Strachan, David P, Curtin, John A, Bønnelykke, Klaus, Tian, Chao, Takahashi, Atsushi, Esparza-Gordillo, Jorge, Alves, Alexessander Couto, Thyssen, Jacob P, den Dekker, Herman T, Ferreira, Manuel A, Altmaier, Elisabeth, Sleiman, Patrick MA, Xiao, Feng Li, Gonzalez, Juan R, Marenholz, Ingo, Kalb, Birgit, Yanes, Maria Pino, Xu, Cheng-Jian, Carstensen, Lisbeth, Groen-Blokhuis, Maria M, Venturini, Cristina, Pennell, Craig E, Barton, Sheila J, Levin, Albert M, Curjuric, Ivan, Bustamante, Mariona, Kreiner-Møller, Eskil, Lockett, Gabrielle A, Bacelis, Jonas, Bunyavanich, Supinda, Myers, Rachel A, Matanovic, Anja, Kumar, Ashish, Tung, Joyce Y, Hirota, Tomomitsu, Kubo, Michiaki, McArdle, Wendy L, Henderson, A J, Kemp, John P, Zheng, Jie, Smith, George Davey, Rüschendorf, Franz, Bauerfeind, Anja, Lee-Kirsch, Min Ae, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Mangold, Elisabeth, Cichon, Sven, Keil, Thomas, Rodríguez, Elke, Peters, Annette, Franke, Andre, Lieb, Wolfgang, Novak, Natalija, Fölster-Holst, Regina, Horikoshi, Momoko, Pekkanen, Juha, Sebert, Sylvain, Husemoen, Lise L, Grarup, Niels, de Jongste, Johan C, Rivadeneira, Fernando, Hofman, Albert, Jaddoe, Vincent WV, Pasmans, Suzanne GMA, Elbert, Niels J, Uitterlinden, André G, Marks, Guy B, Thompson, Philip J, Matheson, Melanie C, Robertson, Colin F, Ried, Janina S, Li, Jin, Zuo, Xian Bo, Zheng, Xiao Dong, Yin, Xian Yong, Sun, Liang Dan, McAleer, Maeve A, O'Regan, Grainne M, Fahy, Caoimhe MR, Campbell, Linda E, Macek, Milan, Kurek, Michael, Hu, Donglei, Eng, Celeste, Postma, Dirkje S, Feenstra, Bjarke, Geller, Frank, Hottenga, Jouke Jan, Middeldorp, Christel M, Hysi, Pirro, Bataille, Veronique, Spector, Tim, Tiesler, Carla MT, Thiering, Elisabeth, Pahukasahasram, Badri, Yang, James J, Imboden, Medea, Huntsman, Scott, Vilor-Tejedor, Natàlia, Relton, Caroline L, Myhre, Ronny, Nystad, Wenche, Custovic, Adnan, Weiss, Scott T, Meyers, Deborah A, Söderhäll, Cilla, Melén, Erik, Ober, Carole, Raby, Benjamin A, Simpson, Angela, Jacobsson, Bo, Holloway, John W, Bisgaard, Hans, Sunyer, Jordi, Hensch, Nicole M Probst, Williams, L Keoki, Godfrey, Keith M, Wang, Carol A, Boomsma, Dorret I, Melbye, Mads, Koppelman, Gerard H, Jarvis, Deborah, McLean, WH Irwin, Irvine, Alan D, Zhang, Xue Jun, Hakonarson, Hakon, Gieger, Christian, Burchard, Esteban G, Martin, Nicholas G, Duijts, Liesbeth, Linneberg, Allan, Jarvelin, Marjo-Riitta, Noethen, Markus M, Lau, Susanne, Hübner, Norbert, Lee, Young-Ae, Tamari, Mayumi, Hinds, David A, Glass, Daniel, Brown, Sara J, Heinrich, Joachim, Evans, David M, Weidinger, Stephan
Publicado no Nat Genet (2015)