Therapeutic Strategies to Inhibit MYC

Por McKeown, Michael R., Bradner, James E.
Publicado em 2014

Improving the photostability of bright monomeric orange and red fluorescent proteins

Por Shaner, Nathan C., Lin, Michael Z., McKeown, Michael R., Steinbach, Paul A., Hazelwood, Kristin L., Davidson, Michael W., Tsien, Roger Y.
Publicado em 2008

Small-Molecule Inhibition of BRDT for Male Contraception

Por Matzuk, Martin M., McKeown, Michael R., Filippakopoulos, Panagis, Li, Qinglei, Ma, Lang, Agno, Julio E., Lemieux, Madeleine E., Picaud, Sarah, Yu, Richard N., Qi, Jun, Knapp, Stefan, Bradner, James E.
Publicado em 2012

Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals

Por Lin, Michael Z., McKeown, Michael R., Ng, Ho-Leung, Aguilera, Todd A., Shaner, Nathan C., Campbell, Robert E., Adams, Stephen R., Gross, Larry A., Ma, Wendy, Alber, Tom, Tsien, Roger Y.
Publicado em 2009

Improving FRET dynamic range with bright green and red fluorescent proteins

Por Lam, Amy, St-Pierre, François, Gong, Yiyang, Marshall, Jesse D., Cranfill, Paula J., Baird, Michelle A., McKeown, Michael R., Wiedenmann, Jörg, Davidson, Michael W., Schnitzer, Mark J., Tsien, Roger Y., Lin, Michael Z.
Publicado em 2012

Biased Multicomponent Reactions to Develop Novel Bromodomain Inhibitors

Por McKeown, Michael R, Shaw, Daniel L, Fu, Harry, Liu, Shuai, Xu, Xiang, Marineau, Jason J, Huang, Yibo, Zhang, Xiaofeng, Buckley, Dennis L, Kadam, Asha, Zhang, Zijuan, Blacklow, Stephen C, Qi, Jun, Zhang, Wei, Bradner, James E
Publicado no J Med Chem (2014)

Discovery and Characterization of Super-Enhancer Associated Dependencies in Diffuse Large B-Cell Lymphoma

Por Chapuy, Bjoern, McKeown, Michael R., Lin, Charles Y., Monti, Stefano, Roemer, Margaretha G.M., Qi, Jun, Rahl, Peter B., Sun, Heather H., Yeda, Kelly T., Doench, John G, Reichert, Elaine, Kung, Andrew L., Rodig, Scott J., Young, Richard A., Shipp, Margaret A., Bradner, James E.
Publicado em 2013

Selective inhibition of BET bromodomains

Por Filippakopoulos, Panagis, Qi, Jun, Picaud, Sarah, Shen, Yao, Smith, William B., Fedorov, Oleg, Morse, Elizabeth M., Keates, Tracey, Hickman, Tyler T., Felletar, Ildiko, Philpott, Martin, Munro, Shonagh, McKeown, Michael R., Wang, Yuchuan, Christie, Amanda L., West, Nathan, Cameron, Michael J., Schwartz, Brian, Heightman, Tom D., La Thangue, Nicholas, French, Christopher A., Wiest, Olaf, Kung, Andrew L., Knapp, Stefan, Bradner, James E.
Publicado em 2010

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Por Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna, McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Publicado em 2011