Extended cell and plasma drug levels after one dose of a 3-in-1 nanosuspension containing lopinavir, efavirenz, and tenofovir in non-human primates

מאת KOEHN, Josefin, IWAMOTO, Jennifer F., KRAFT, John C., McCONNACHIE, Lisa A., COLLIER, Ann C., HO, Rodney J.Y.
הוצא לאור ב AIDS (2018)

Novel drug combination nanoparticles exhibit enhanced plasma exposure and dose-responsive effects on eliminating breast cancer lung metastasis

מאת Mu, Qingxin, Yu, Jesse, Griffin, James I., Wu, Yan, Zhu, Linxi, McConnachie, Lisa A., Ho, Rodney J. Y.
הוצא לאור ב PLoS One (2020)

Lack of Maternal Glutamate Cysteine Ligase Modifier Subunit (Gclm) Decreases Oocyte Glutathione Concentrations and Disrupts Preimplantation Development in Mice

מאת Nakamura, Brooke N., Fielder, Thomas J., Hoang, Yvonne D., Lim, Jinhwan, McConnachie, Lisa A., Kavanagh, Terrance J., Luderer, Ulrike
יצא לאור 2011

Translation of combination nanodrugs into nanomedicines: lessons learned and future outlook

מאת Mu, Qingxin, Yu, Jesse, McConnachie, Lisa A., Kraft, John C., Gao, Yu, Gulati, Gaurav K., Ho, Rodney J. Y.
הוצא לאור ב J Drug Target (2018)

Three HIV Drugs, Atazanavir, Ritonavir, and Tenofovir, Coformulated in Drug-Combination Nanoparticles Exhibit Long-Acting and Lymphocyte-Targeting Properties in Nonhuman Primates

מאת Perazzolo, Simone, Shireman, Laura M., Koehn, Josefin, McConnachie, Lisa A., Kraft, John C., Shen, Danny D., Ho, Rodney J.Y.
הוצא לאור ב J Pharm Sci (2018)

Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma

מאת Kraft, John C., McConnachie, Lisa A., Koehn, Josefin, Kinman, Loren, Collins, Carol, Shen, Danny D., Collier, Ann C., Ho, Rodney J.Y.
הוצא לאור ב AIDS (2017)

Long-Acting Profile of 4 Drugs in 1 Anti-HIV Nanosuspension in Nonhuman Primates for 5 Weeks After a Single Subcutaneous Injection

מאת McConnachie, Lisa A., Kinman, Loren M., Koehn, Josefin, Kraft, John C., Lane, Sarah, Lee, Wonsok, Collier, Ann C., Ho, Rodney J.Y.
הוצא לאור ב J Pharm Sci (2018)

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formul...

מאת Kraft, John C., McConnachie, Lisa A., Koehn, Josefin, Kinman, Loren, Sun, Jianguo, Collier, Ann C., Collins, Carol, Shen, Danny D., Ho, Rodney J. Y.
הוצא לאור ב J Control Release (2018)

Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots

מאת McConnachie, Lisa A., White, Collin C., Botta, Dianne, Zadworny, Megan E., Cox, David P., Beyer, Richard P., Hu, Xiaoge, Eaton, David L., Gao, Xiaohu, Kavanagh, Terrance J.
יצא לאור 2012

Increased Sensitivity to Testicular Toxicity of Transplacental Benzo[a]pyrene Exposure in Male Glutamate Cysteine Ligase Modifier Subunit Knockout (Gclm−/−) Mice

מאת Nakamura, Brooke N., Mohar, Isaac, Lawson, Gregory W., Cortés, Mabel M., Hoang, Yvonne D., Ortiz, Laura, Patel, Reshma, Rau, Bogdan A., McConnachie, Lisa A., Kavanagh, Terrance J., Luderer, Ulrike
יצא לאור 2012

The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot–Induced Lung Inflammation in Mice

מאת McConnachie, Lisa A., Botta, Dianne, White, Collin C., Weldy, Chad S., Wilkerson, Hui-Wen, Yu, Jianbo, Dills, Russell, Yu, Xiaozhong, Griffith, William C., Faustman, Elaine M., Farin, Federico M., Gill, Sean E., Parks, William C., Hu, Xiaoge, Gao, Xiaohu, Eaton, David L., Kavanagh, Terrance J.
יצא לאור 2013

Susceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strains

מאת Scoville, David K., White, Collin C., Botta, Dianne, McConnachie, Lisa A., Zadworny, Megan E., Schmuck, Stefanie C., Hu, Xiaoge, Gao, Xiaohu, Yu, Jianbo, Dills, Russell L., Sheppard, Lianne, Delaney, Martha A., Griffith, William C., Beyer, Richard P., Zangar, Richard C., Pounds, Joel G., Faustman, Elaine M., Kavanagh, Terrance J.
הוצא לאור ב Toxicol Appl Pharmacol (2015)