Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip()

Por Grosberg, Anna, Alford, Patrick W., McCain, Megan L., Parker, Kevin Kit
Publicado em 2011

Human Airway Musculature on a Chip: An In Vitro Model of Allergic Asthmatic Bronchoconstriction and Bronchodilation

Por Nesmith, Alexander P., Agarwal, Ashutosh, McCain, Megan L., Parker, Kevin Kit
Publicado em 2014

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility

Por McCain, Megan L., Yuan, Hongyan, Pasqualini, Francesco S., Campbell, Patrick H., Parker, Kevin Kit
Publicado em 2014

Cooperative coupling of cell-matrix and cell–cell adhesions in cardiac muscle

Por McCain, Megan L., Lee, Hyungsuk, Aratyn-Schaus, Yvonne, Kléber, André G., Parker, Kevin Kit
Publicado em 2012

Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip

Por McCain, Megan L., Sheehy, Sean P., Grosberg, Anna, Goss, Josue A., Parker, Kevin Kit
Publicado em 2013

Micromolded Gelatin Hydrogels for Extended Culture of Engineered Cardiac Tissues

Por McCain, Megan L., Agarwal, Ashutosh, Nesmith, Haley W., Nesmith, Alexander P., Parker, Kevin Kit
Publicado em 2014

Connexin 43 Expression Delineates Two Discrete Pathways in the Human Atrioventricular Junction

Por HUCKER, WILLIAM J., McCAIN, MEGAN L., LAUGHNER, JACOB I., IAIZZO, PAUL A., EFIMOV, IGOR R.
Publicado em 2008

Muscle on a Chip: In Vitro Contractility Assays for Smooth and Striated Muscle

Por Grosberg, Anna, Nesmith, Alexander P., Goss, Josue A., Brigham, Mark D., McCain, Megan L., Parker, Kevin Kit
Publicado em 2012

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

Por Desplantez, Thomas, McCain, Megan L., Beauchamp, Philippe, Rigoli, Ghislaine, Rothen-Rutishauser, Barbara, Parker, Kevin Kit, Kleber, Andre G.
Publicado em 2012

Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance

Por McCain, Megan L., Desplantez, Thomas, Geisse, Nicholas A., Rothen-Rutishauser, Barbara, Oberer, Helene, Parker, Kevin Kit, Kleber, Andre G.
Publicado em 2012

ELECTRICAL COUPLING AND PROPAGATION IN ENGINEERED VENTRICULAR MYOCARDIUM WITH HETEROGENEOUS EXPRESSION OF CONNEXIN43

Por Beauchamp, Philippe, Desplantez, Thomas, McCain, Megan L., Li, Weihui, Asimaki, Angeliki, Rigoli, Ghislaine, Parker, Kevin Kit, Saffitz, Jeffrey E., Kleber, Andre G.
Publicado em 2012

A tissue-engineered jellyfish with biomimetic propulsion

Por Nawroth, Janna C, Lee, Hyungsuk, Feinberg, Adam W, Ripplinger, Crystal M, McCain, Megan L, Grosberg, Anna, Dabiri, John O, Parker, Kevin Kit
Publicado em 2012

Angiotensin II Induced Cardiac Dysfunction on a Chip

Por Horton, Renita E., Yadid, Moran, McCain, Megan L., Sheehy, Sean P., Pasqualini, Francesco S., Park, Sung-Jin, Cho, Alexander, Campbell, Patrick, Parker, Kevin Kit
Publicado no PLoS One (2016)

Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy

Por Aratyn-Schaus, Yvonne, Pasqualini, Francesco S., Yuan, Hongyan, McCain, Megan L., Ye, George J.C., Sheehy, Sean P., Campbell, Patrick H., Parker, Kevin Kit
Publicado no J Cell Biol (2016)

Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes

Por Lee, Hyungsuk, Adams, William J, Alford, Patrick W, McCain, Megan L, Feinberg, Adam W, Sheehy, Sean P, Goss, Josue A, Parker, Kevin Kit
Publicado no Exp Biol Med (Maywood) (2015)

Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy

Por Aratyn-Schaus, Yvonne, Pasqualini, Francesco S., Yuan, Hongyan, McCain, Megan L., Ye, George J.C., Sheehy, Sean P., Campbell, Patrick H., Parker, Kevin Kit
Publicado no J Exp Med (2016)

Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment

Por Lyra-Leite, Davi M., Andres, Allen M., Petersen, Andrew P., Ariyasinghe, Nethika R., Cho, Nathan, Lee, Jezell A., Gottlieb, Roberta A., McCain, Megan L.
Publicado no Am J Physiol Heart Circ Physiol (2017)

Prolonged Culture of Aligned Skeletal Myotubes on Micromolded Gelatin Hydrogels

Por Bettadapur, Archana, Suh, Gio C., Geisse, Nicholas A., Wang, Evelyn R., Hua, Clara, Huber, Holly A., Viscio, Alyssa A., Kim, Joon Young, Strickland, Julie B., McCain, Megan L.
Publicado no Sci Rep (2016)

Modeling the mitochondrial cardiomyopathy of Barth syndrome with iPSC and heart-on-chip technologies

Por Wang, Gang, McCain, Megan L., Yang, Luhan, He, Aibin, Pasqualini, Francesco Silvio, Agarwal, Ashutosh, Yuan, Hongyan, Jiang, Dawei, Zhang, Donghui, Zangi, Lior, Geva, Judith, Roberts, Amy E., Ma, Qing, Ding, Jian, Chen, Jinghai, Wang, Da-zhi, Li, Kai, Wang, Jiwu, Wanders, Ronald J. A., Kulik, Wim, Vaz, Frédéric M., Laflamme, Michael A., Murry, Charles E., Chien, Kenneth R., Kelley, Richard I., Church, George M., Parker, Kevin Kit, Pu, William T.
Publicado em 2014