Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance

Gap junctions are composed of connexin (Cx) proteins, which mediate intercellular communication. Cx43 is the dominant Cx in ventricular myocardium, and Cx45 is present in trace amounts. Cx43 immunosignal has been associated with cell-to-cell coupling and electrical propagation, but no studies have d...

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Bibliografiske detaljer
Main Authors: McCain, Megan L., Desplantez, Thomas, Geisse, Nicholas A., Rothen-Rutishauser, Barbara, Oberer, Helene, Parker, Kevin Kit, Kleber, Andre G.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Cardiac Excitation and Contraction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339855/
https://ncbi.nlm.nih.gov/pubmed/22081700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01218.2010
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