Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment

Mitochondria in cardiac myocytes are critical for generating ATP to meet the high metabolic demands associated with sarcomere shortening. Distinct remodeling of mitochondrial structure and function occur in cardiac myocytes in both developmental and pathological settings. However, the factors that u...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Lyra-Leite, Davi M., Andres, Allen M., Petersen, Andrew P., Ariyasinghe, Nethika R., Cho, Nathan, Lee, Jezell A., Gottlieb, Roberta A., McCain, Megan L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668604/
https://ncbi.nlm.nih.gov/pubmed/28733449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00290.2017
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