Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment

Mitochondria in cardiac myocytes are critical for generating ATP to meet the high metabolic demands associated with sarcomere shortening. Distinct remodeling of mitochondrial structure and function occur in cardiac myocytes in both developmental and pathological settings. However, the factors that u...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Lyra-Leite, Davi M., Andres, Allen M., Petersen, Andrew P., Ariyasinghe, Nethika R., Cho, Nathan, Lee, Jezell A., Gottlieb, Roberta A., McCain, Megan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668604/
https://ncbi.nlm.nih.gov/pubmed/28733449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00290.2017
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