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Engineering cardiac microphysiological systems to model pathological extracellular matrix remodeling

Many cardiovascular diseases are associated with pathological remodeling of the extracellular matrix (ECM) in the myocardium. ECM remodeling is a complex, multifactorial process that often contributes to declines in myocardial function and progression toward heart failure. However, the direct effect...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Ariyasinghe, Nethika R., Lyra-Leite, Davi M., McCain, Megan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230901/
https://ncbi.nlm.nih.gov/pubmed/29906229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00110.2018
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