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Human Airway Musculature on a Chip: An In Vitro Model of Allergic Asthmatic Bronchoconstriction and Bronchodilation

Many potential new asthma therapies that show promise in the pre-clinical stage of drug development do not demonstrate efficacy during clinical trials. One factor contributing to this problem is the lack of human-relevant models of the airway that recapitulate the tissue-level structural and functio...

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Main Authors: Nesmith, Alexander P., Agarwal, Ashutosh, McCain, Megan L., Parker, Kevin Kit
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167568/
https://ncbi.nlm.nih.gov/pubmed/25093641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4lc00688g
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