An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis

door Mahtouk, Karène, Jourdan, Michel, De Vos, John, Hertogh, Catherine, Fiol, Geneviève, Jourdan, Eric, Rossi, Jean-François, Klein, Bernard
Gepubliceerd in 2004

Transcriptional Silencing of the Wnt-Antagonist DKK1 by Promoter Methylation Is Associated with Enhanced Wnt Signaling in Advanced Multiple Myeloma

door Kocemba, Kinga A., Groen, Richard W. J., van Andel, Harmen, Kersten, Marie José, Mahtouk, Karène, Spaargaren, Marcel, Pals, Steven T.
Gepubliceerd in 2012

Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications

door Mahtouk, Karène, Hose, Dirk, De Vos, John, Moreaux, Jérôme, Jourdan, Michel, Rossi, Jean François, Rème, Thierry, Goldschmidt, Harmut, Klein, Bernard
Gepubliceerd in 2007

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

door Mahtouk, Karène, Moreaux, Jérôme, Hose, Dirk, Rème, Thierry, Meißner, Tobias, Jourdan, Michel, Rossi, Jean François, Pals, Steven T, Goldschmidt, Hartmut, Klein, Bernard
Gepubliceerd in 2010

Bone marrow mesenchymal stem cells are abnormal in multiple myeloma

door Corre, Jill, Mahtouk, Karène, Attal, Michel, Gadelorge, Mélanie, Huynh, Anne, Fleury-Cappellesso, Sandrine, Danho, Clotaire, Laharrague, Patrick, Klein, Bernard, Rème, Thierry, Bourin, Philippe
Gepubliceerd in 2007

Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells

door Bret, Caroline, Hose, Dirk, Reme, Thierry, Sprynski, Anne-Catherine, Mahtouk, Karène, Schved, Jean-François, Quittet, Philippe, Rossi, Jean-François, Goldschmidt, Hartmut, Klein, Bernard
Gepubliceerd in 2009

Microarray-based understanding of normal and malignant plasma cells

door De Vos, John, Hose, Dirk, Rème, Thierry, Tarte, Karin, Moreaux, Jérôme, Mahtouk, Karéne, Jourdan, Michel, Goldschmidt, Hartmut, Rossi, Jean-François, Cremer, Friedrich W., Klein, Bernard
Gepubliceerd in 2006

Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A(1)

door Salvatore, Giulia, Bernoud-Hubac, Nathalie, Bissay, Nathalie, Debard, Cyrille, Daira, Patricia, Meugnier, Emmanuelle, Proamer, Fabienne, Hanau, Daniel, Vidal, Hubert, Aricò, Maurizio, Delprat, Christine, Mahtouk, Karène
Gepubliceerd in J Lipid Res (2015)

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

door Jourdan, Michel, Moreaux, Jérôme, Vos, John De, Hose, Dirk, Mahtouk, Karène, Abouladze, Matthieu, Robert, Nicolas, Baudard, Marion, Rème, Thierry, Romanelli, Angela, Goldschmidt, Hartmut, Rossi, Jean-François, Dreano, Michel, Klein, Bernard
Gepubliceerd in 2007

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

door Mahtouk, Karène, Hose, Dirk, Raynaud, Pierre, Hundemer, Michael, Jourdan, Michel, Jourdan, Eric, Pantesco, Véronique, Baudard, Marion, De Vos, John, Larroque, Marion, Moehler, Thomas, Rossi, Jean-François, Reme, Thierry, Goldschmidt, Hartmut, Klein, Bernard
Gepubliceerd in 2007

Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma

door Mahtouk, Karène, Cremer, Friedrich W., Rème, Thierry, Jourdan, Michel, Baudard, Marion, Moreaux, Jérome, Requirand, Guilhem, Fiol, Geneviève, De Vos, John, Moos, Marion, Quittet, Philippe, Goldschmidt, Hartmut, Rossi, Jean-François, Hose, Dirk, Klein, Bernard
Gepubliceerd in 2006

Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells

door Mahtouk, Karène, Hose, Dirk, Rème, Thierry, De Vos, John, Jourdan, Michel, Moreaux, Jérôme, Fiol, Geneviève, Raab, Marc, Jourdan, Eric, Grau, Véronique, Moos, Marion, Goldschmidt, Hartmut, Baudard, Marion, Rossi, Jean François, Cremer, Friedrich W., Klein, Bernard
Gepubliceerd in 2005

The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature

door Moreaux, Jérôme, Cremer, Friedrich W., Reme, Thierry, Raab, Marc, Mahtouk, Karene, Kaukel, Philine, Pantesco, Veronique, De Vos, John, Jourdan, Eric, Jauch, Anna, Legouffe, Eric, Moos, Marion, Fiol, Genevieve, Goldschmidt, Hartmut, Rossi, Jean François, Hose, Dirk, Klein, Bernard
Gepubliceerd in 2005

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

door Sprynski, Anne Catherine, Hose, Dirk, Caillot, Laurent, Rème, Thierry, Shaughnessy, John D., Barlogie, Bart, Seckinger, Anja, Moreaux, Jérôme, Hundemer, Michael, Jourdan, Michel, Meissner, Tobias, Jauch, Anna, Mahtouk, Karene, Kassambara, Alboukadel, Bertsch, Uta, Rossi, Jean-François, Goldschmidt, Hartmut, Klein, Bernard
Gepubliceerd in 2009

Genetic evidence of a precisely tuned dysregulation in the hypoxia signaling pathway during oncogenesis

door Couvé, Sophie, Ladroue, Charline, Laine, Elodie, Mahtouk, Karène, Guégan, Justine, Gad, Sophie, Le Jeune, Hélène, Le Gentil, Marion, Nuel, Gregory, Kim, William Y., Lecomte, Bernard, Pagès, Jean-Christophe, Collin, Christine, Lasne, Françoise, Benusiglio, Patrick R., Bressac-de Paillerets, Brigitte, Feunteun, Jean, Lazar, Vladimir, Gimenez-Roqueplo, Anne-Paule, Mazure, Nathalie M., Dessen, Philippe, Tchertanov, Luba, Mole, David, Kaelin, William, Ratcliffe, Peter, Richard, Stéphane, Gardie, Betty
Gepubliceerd in Cancer Res (2014)