Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

The pathophysiologic basis for multiple myeloma (MM) has been attributed to the dysregulation of various paracrine or autocrine growth factor loops and to perturbations in several signal transduction pathways including IKK/NF-κB. The aim of the present study was to investigate the effect of a pharma...

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Autores principales: Jourdan, Michel, Moreaux, Jérôme, Vos, John De, Hose, Dirk, Mahtouk, Karène, Abouladze, Matthieu, Robert, Nicolas, Baudard, Marion, Rème, Thierry, Romanelli, Angela, Goldschmidt, Hartmut, Rossi, Jean-François, Dreano, Michel, Klein, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Scientific Publications 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494583/
https://ncbi.nlm.nih.gov/pubmed/17542984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2007.06629.x
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