Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

The pathophysiologic basis for multiple myeloma (MM) has been attributed to the dysregulation of various paracrine or autocrine growth factor loops and to perturbations in several signal transduction pathways including IKK/NF-κB. The aim of the present study was to investigate the effect of a pharma...

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Main Authors: Jourdan, Michel, Moreaux, Jérôme, Vos, John De, Hose, Dirk, Mahtouk, Karène, Abouladze, Matthieu, Robert, Nicolas, Baudard, Marion, Rème, Thierry, Romanelli, Angela, Goldschmidt, Hartmut, Rossi, Jean-François, Dreano, Michel, Klein, Bernard
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Scientific Publications 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494583/
https://ncbi.nlm.nih.gov/pubmed/17542984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2007.06629.x
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