In Vivo Model of Small Intestine

Por Mahe, Maxime M., Brown, Nicole E., Poling, Holly M., Helmrath, Michael A.
Publicado no Methods Mol Biol (2017)

The omega-6 fatty acid derivative 15-deoxy-Δ(12,14)-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress

Por Abdo, Hind, Mahé, Maxime M, Derkinderen, Pascal, Bach-Ngohou, Kalyane, Neunlist, Michel, Lardeux, Bernard
Publicado em 2012

Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy

Por Mahe, Maxime M., Sundaram, Nambirajan, Watson, Carey L., Shroyer, Noah F., Helmrath, Michael A.
Publicado no J Vis Exp (2015)

Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

Por Van Landeghem, Laurianne, Mahé, Maxime M, Teusan, Raluca, Léger, Jean, Guisle, Isabelle, Houlgatte, Rémi, Neunlist, Michel
Publicado em 2009

Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes

Por Lobeck, Inna, Donnelly, Bryan, Dupree, Phylicia, Mahe, Maxime M., McNeal, Monica, Mohanty, Sujit K., Tiao, Greg
Publicado no Virology (2016)

Enteric glia promote intestinal mucosal healing via activation of focal adhesion kinase and release of proEGF

Por Van Landeghem, Laurianne, Chevalier, Julien, Mahé, Maxime M., Wedel, Thilo, Urvil, Petri, Derkinderen, Pascal, Savidge, Tor, Neunlist, Michel
Publicado em 2011

Establishment of gastrointestinal epithelial organoids

Por Mahé, Maxime M, Aihara, Eitaro, Schumacher, Michael A., Zavros, Yana, Montrose, Marshall H., Helmrath, Michael A, Sato, Toshiro, Shroyer, Noah F
Publicado em 2013

Enteric glia modulate epithelial cell proliferation and differentiation through 15-deoxy-Δ(12,14)-prostaglandin J2

Por Bach-Ngohou, Kalyane, Mahé, Maxime M, Aubert, Philippe, Abdo, Hind, Boni, Sébastien, Bourreille, Arnaud, Denis, Marc G, Lardeux, Bernard, Neunlist, Michel, Masson, Damien
Publicado em 2010

Glutamine and alanyl-glutamine promote crypt expansion and mTOR signaling in murine enteroids

Por Moore, Sean R., Guedes, Marjorie M., Costa, Tie B., Vallance, Jefferson, Maier, Elizabeth A., Betz, Kristina J., Aihara, Eitaro, Mahe, Maxime M., Lima, Aldo A. M., Oriá, Reinaldo B., Shroyer, Noah F.
Publicado no Am J Physiol Gastrointest Liver Physiol (2015)

Intestinal stem cells remain viable after prolonged tissue storage

Por Fuller, Megan K., Faulk, Denver M., Sundaram, Nambirajan, Mahe, Maxime M., Stout, Kara M., von Furstenberg, Richard J., Smith, Brian J., McNaughton, Kirk K., Shroyer, Noah F., Helmrath, Michael A., Henning, Susan J.
Publicado em 2013

CD44 Plays a Functional Role in Helicobacter pylori-induced Epithelial Cell Proliferation

Por Bertaux-Skeirik, Nina, Feng, Rui, Schumacher, Michael A., Li, Jing, Mahe, Maxime M., Engevik, Amy C., Javier, Jose E., Peek Jr, Richard M., Ottemann, Karen, Orian-Rousseau, Veronique, Boivin, Gregory P., Helmrath, Michael A., Zavros, Yana
Publicado no PLoS Pathog (2015)

Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine

Por Lo, Yuan-Hung, Chung, Eunah, Li, Zhaohui, Wan, Ying-Wooi, Mahe, Maxime M., Chen, Min-Shan, Noah, Taeko K., Bell, Kristin N., Yalamanchili, Hari Krishna, Klisch, Tiemo J., Liu, Zhandong, Park, Joo-Seop, Shroyer, Noah F.
Publicado no Cell Mol Gastroenterol Hepatol (2016)

An in vivo model of human small intestine using pluripotent stem cells

Por Watson, Carey L, Mahe, Maxime M, Múnera, Jorge, Howell, Jonathan C, Sundaram, Nambirajan, Poling, Holly M, Schweitzer, Jamie I, Vallance, Jefferson E, Mayhew, Christopher N, Sun, Ying, Grabowski, Gregory, Finkbeiner, Stacy R, Spence, Jason R, Shroyer, Noah F, Wells, James M, Helmrath, Michael A
Publicado no Nat Med (2014)

Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid

Por Aihara, Eitaro, Mahe, Maxime M., Schumacher, Michael A., Matthis, Andrea L., Feng, Rui, Ren, Wenwen, Noah, Taeko K., Matsu-ura, Toru, Moore, Sean R., Hong, Christian I., Zavros, Yana, Herness, Scott, Shroyer, Noah F., Iwatsuki, Ken, Jiang, Peihua, Helmrath, Michael A., Montrose, Marshall H.
Publicado no Sci Rep (2015)

The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach

Por Engevik, Amy C., Feng, Rui, Choi, Eunyoung, White, Shana, Bertaux-Skeirik, Nina, Li, Jing, Mahe, Maxime M., Aihara, Eitaro, Yang, Li, DiPasquale, Betsy, Oh, Sunghee, Engevik, Kristen A., Giraud, Andrew S., Montrose, Marshall H., Medvedovic, Mario, Helmrath, Michael A., Goldenring, James R., Zavros, Yana
Publicado no Cell Mol Gastroenterol Hepatol (2016)

CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium

Por Bertaux-Skeirik, Nina, Wunderlich, Mark, Teal, Emma, Chakrabarti, Jayati, Biesiada, Jacek, Mahe, Maxime, Sundaram, Nambirajan, Gabre, Joel, Hawkins, Jennifer, Jian, Gao, Engevik, Amy C., Yang, Li, Wang, Jiang, Goldenring, James R., Qualls, Joseph E., Medvedovic, Mario, Helmrath, Michael A., Diwan, Tayyab, Mulloy, James C., Zavros, Yana
Publicado no J Pathol (2017)

Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling

Por Múnera, Jorge O., Sundaram, Nambirajan, Rankin, Scott A., Hill, David, Watson, Carey, Mahe, Maxime, Vallance, Jefferson E., Shroyer, Noah F., Sinagoga, Katie L., Zarsozo-Lacoste, Adrian, Hudson, Jonathan R., Howell, Jonathan C., Chatuvedi, Praneet, Spence, Jason R., Shannon, John M., Zorn, Aaron M., Helmrath, Michael, Wells, James M.
Publicado no Cell Stem Cell (2017)

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

Por Workman, Michael J, Mahe, Maxime M, Trisno, Stephen, Poling, Holly M, Watson, Carey L, Sundaram, Nambirajan, Chang, Ching-Fang, Schiesser, Jacqueline, Aubert, Philippe, Stanley, Edouard G, Elefanty, Andrew G, Miyaoka, Yuichiro, Mandegar, Mohammad A, Conklin, Bruce R, Neunlist, Michel, Brugmann, Samantha A, Helmrath, Michael A, Wells, James M
Publicado no Nat Med (2016)

Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-Formation Assay

Por WANG, FENGCHAO, SCOVILLE, DAVID, HE, XI C., MAHE, MAXIME M., BOX, ANDREW, PERRY, JOHN M., SMITH, NICHOLAS R., LEI, NAN YE, DAVIES, PAIGE S., FULLER, MEGAN K., HAUG, JEFFREY S., MCCLAIN, MELAINIA, GRACZ, ADAM D., DING, SHENG, STELZNER, MATTHIAS, DUNN, JAMES C. Y., MAGNESS, SCOTT T., WONG, MELISSA H., MARTIN, MARTIN G., HELMRATH, MICHAEL, LI, LINHENG
Publicado em 2013

Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo

Por Finkbeiner, Stacy R., Hill, David R., Altheim, Christopher H., Dedhia, Priya H., Taylor, Matthew J., Tsai, Yu-Hwai, Chin, Alana M., Mahe, Maxime M., Watson, Carey L., Freeman, Jennifer J., Nattiv, Roy, Thomson, Matthew, Klein, Ophir D., Shroyer, Noah F., Helmrath, Michael A., Teitelbaum, Daniel H., Dempsey, Peter J., Spence, Jason R.
Publicado no Stem Cell Reports (2015)