Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-Formation Assay

BACKGROUND & AIMS: Identification of intestinal stem cells (ISCs) has relied heavily on the use of transgenic reporters in mice, but this approach is limited by mosaic expression patterns and difficult to directly apply to human tissues. We sought to identify reliable surface markers of ISCs and...

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Main Authors: WANG, FENGCHAO, SCOVILLE, DAVID, HE, XI C., MAHE, MAXIME M., BOX, ANDREW, PERRY, JOHN M., SMITH, NICHOLAS R., LEI, NAN YE, DAVIES, PAIGE S., FULLER, MEGAN K., HAUG, JEFFREY S., MCCLAIN, MELAINIA, GRACZ, ADAM D., DING, SHENG, STELZNER, MATTHIAS, DUNN, JAMES C. Y., MAGNESS, SCOTT T., WONG, MELISSA H., MARTIN, MARTIN G., HELMRATH, MICHAEL, LI, LINHENG
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781924/
https://ncbi.nlm.nih.gov/pubmed/23644405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.04.050
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