Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling

Gastric and small intestinal organoids differentiated from human pluripotent stem cells (hPSCs) have revolutionized the study of gastrointestinal development and disease. Distal gut tissues such as cecum and colon, however, have proven considerably more challenging to derive in vitro. Here we report...

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Publicado no:Cell Stem Cell
Main Authors: Múnera, Jorge O., Sundaram, Nambirajan, Rankin, Scott A., Hill, David, Watson, Carey, Mahe, Maxime, Vallance, Jefferson E., Shroyer, Noah F., Sinagoga, Katie L., Zarsozo-Lacoste, Adrian, Hudson, Jonathan R., Howell, Jonathan C., Chatuvedi, Praneet, Spence, Jason R., Shannon, John M., Zorn, Aaron M., Helmrath, Michael, Wells, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531599/
https://ncbi.nlm.nih.gov/pubmed/28648364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.05.020
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