Confab - Systematic generation of diverse low-energy conformers

Por O'Boyle, Noel M, Vandermeersch, Tim, Flynn, Christopher J, Maguire, Anita R, Hutchison, Geoffrey R
Publicado em 2011

Conformational states of HIV-1 reverse transcriptase for nucleotide incorporation vs. pyrophosphorolysis – binding of foscarnet

Por Das, Kalyan, Balzarini, Jan, Miller, Matthew T., Maguire, Anita R., DeStefano, Jeffrey J., Arnold, Eddy
Publicado no ACS Chem Biol (2016)

Exploring the role of the α-carboxyphosphonate moiety in the HIV-RT activity of α-carboxy nucleoside phosphonates

Por Mullins, Nicholas D., Maguire, Nuala M., Ford, Alan, Das, Kalyan, Arnold, Edward, Balzarini, Jan, Maguire, Anita R.
Publicado no Org Biomol Chem (2016)

Development of a continuous process for α-thio-β-chloroacrylamide synthesis with enhanced control of a cascade transformation

Por Dennehy, Olga C, Cacheux, Valérie M Y, Deadman, Benjamin J, Lynch, Denis, Collins, Stuart G, Moynihan, Humphrey A, Maguire, Anita R
Publicado no Beilstein J Org Chem (2016)

The impact of storage conditions upon gentamicin coated antimicrobial implants()

Por Mullins, Nicholas D., Deadman, Benjamin J., Moynihan, Humphrey A., McCarthy, Florence O., Lawrence, Simon E., Thompson, Jonathan, Maguire, Anita R.
Publicado no J Pharm Anal (2016)

Pronounced inhibition shift from HIV reverse transcriptase to herpetic DNA polymerases by increasing the flexibility of α-carboxy nucleoside phosphonates (α-CNP)

Por John, Jubi, Kim, Youngju, Bennett, Nicholas, Das, Kalyan, Liekens, Sandra, Naesens, Lieve, Arnold, Eddy, Maguire, Anita R., Götte, Matthias, Dehaen, Wim, Balzarini, Jan
Publicado no J Med Chem (2015)

Guanine α-carboxy nucleoside phosphonate (G-α-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency virus (HIV) and herpes viruses...

Por Balzarini, Jan, Menni, Michael, Das, Kalyan, van Berckelaer, Lizette, Ford, Alan, Maguire, Nuala M., Liekens, Sandra, Boehmer, Paul E., Arnold, Eddy, Götte, Matthias, Maguire, Anita R.
Publicado no Biochem Pharmacol (2017)

Evaluation of the Bruker SMART X2S: crystallography for the nonspecialist?

Por Eccles, Kevin S., Stokes, Stephen P., Daly, Carla A., Barry, Nicola M., McSweeney, Sharon P., O’Neill, Damian J., Kelly, Dawn M., Jennings, W. Brian, Ní Dhubhghaill, O. M., Moynihan, Humphrey A., Maguire, Anita R., Lawrence, Simon E.
Publicado em 2011

Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics

Por Balzarini, Jan, Das, Kalyan, Bernatchez, Jean A., Martinez, Sergio E., Ngure, Marianne, Keane, Sarah, Ford, Alan, Maguire, Nuala, Mullins, Niki, John, Jubi, Kim, Youngju, Dehaen, Wim, Vande Voorde, Johan, Liekens, Sandra, Naesens, Lieve, Götte, Matthias, Maguire, Anita R., Arnold, Eddy
Publicado no Proc Natl Acad Sci U S A (2015)