Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

Por Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.
Publicado no Mol Cell (2016)

Metabolic Regulation by p53 Family Members

Por Berkers, Celia R., Maddocks, Oliver D.K., Cheung, Eric C., Mor, Inbal, Vousden, Karen H.
Publicado em 2013

iRFP is a sensitive marker for cell number and tumor growth in high-throughput systems

Por Hock, Andreas K, Lee, Pearl, Maddocks, Oliver DK, Mason, Susan M, Blyth, Karen, Vousden, Karen H
Publicado em 2014

Polyamine pathway activity promotes cysteine essentiality in cancer cells

Por Zhang, Tong, Bauer, Christin, Newman, Alice C., Uribe, Alejandro Huerta, Athineos, Dimitris, Blyth, Karen, Maddocks, Oliver D.K.
Publicado no Nat Metab (2020)

A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila

Por Scopelliti, Alessandro, Bauer, Christin, Yu, Yachuan, Zhang, Tong, Kruspig, Björn, Murphy, Daniel J., Vidal, Marcos, Maddocks, Oliver D.K., Cordero, Julia B.
Publicado no Cell Metab (2019)

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Por Carroll, Bernadette, Maetzel, Dorothea, Maddocks, Oliver DK, Otten, Gisela, Ratcliff, Matthew, Smith, Graham R, Dunlop, Elaine A, Passos, João F, Davies, Owen R, Jaenisch, Rudolf, Tee, Andrew R, Sarkar, Sovan, Korolchuk, Viktor I
Publicado no eLife (2016)

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Por Carroll, Bernadette, Maetzel, Dorothea, Maddocks, Oliver DK, Otten, Gisela, Ratcliff, Matthew, Smith, Graham R, Dunlop, Elaine A, Passos, João F, Davies, Owen Richard, Jaenisch, Rudolf, Tee, Andrew R, Sarkar, Sovan, Korolchuk, Viktor I
Publicado no eLife (2020)

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Por Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C.L., Maddocks, Oliver D.K., Chokkathukalam, Achuthanunni, Coyle, Joseph E, Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal
Publicado em 2012

PHD1 regulates p53-mediated colorectal cancer chemoresistance

Por Deschoemaeker, Sofie, Di Conza, Giusy, Lilla, Sergio, Martín-Pérez, Rosa, Mennerich, Daniela, Boon, Lise, Hendrikx, Stefanie, Maddocks, Oliver DK, Marx, Christian, Radhakrishnan, Praveen, Prenen, Hans, Schneider, Martin, Myllyharju, Johanna, Kietzmann, Thomas, Vousden, Karen H, Zanivan, Sara, Mazzone, Massimiliano
Publicado no EMBO Mol Med (2015)

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing

Por Carroll, Bernadette, Nelson, Glyn, Rabanal-Ruiz, Yoana, Kucheryavenko, Olena, Dunhill-Turner, Natasha A., Chesterman, Charlotte C., Zahari, Qabil, Zhang, Tong, Conduit, Sarah E., Mitchell, Christina A., Maddocks, Oliver D.K., Lovat, Penny, von Zglinicki, Thomas, Korolchuk, Viktor I.
Publicado no J Cell Biol (2017)

mTORC1 activity is supported by spatial association with focal adhesions

Por Rabanal-Ruiz, Yoana, Byron, Adam, Wirth, Alexander, Madsen, Ralitsa, Sedlackova, Lucia, Hewitt, Graeme, Nelson, Glyn, Stingele, Julian, Wills, Jimi C., Zhang, Tong, Zeug, André, Fässler, Reinhard, Vanhaesebroeck, Bart, Maddocks, Oliver D.K., Ponimaskin, Evgeni, Carroll, Bernadette, Korolchuk, Viktor I.
Publicado no J Cell Biol (2021)

Assessment of tumor redox status through (S)-4-(3-[(18)F]fluoropropyl)-l-glutamic acid positron emission tomography imaging of system x(c)(-) activity

Por McCormick, Patrick N., Greenwood, Hannah E., Glaser, Matthias, Maddocks, Oliver D.K., Gendron, Thibault, Sander, Kerstin, Gowrishankar, Gayatri, Hoehne, Aileen, Zhang, Tong, Shuhendler, Adam J., Lewis, David Y., Berndt, Mathias, Koglin, Norman, Lythgoe, Mark F., Gambhir, Sanjiv S., Årstad, Erik, Witney, Timothy H.
Publicado no Cancer Res (2018)