Assessment of tumor redox status through (S)-4-(3-[(18)F]fluoropropyl)-l-glutamic acid positron emission tomography imaging of system x(c)(-) activity

The cell's endogenous antioxidant system is vital to maintenance of redox homeostasis. Despite its central role in normal and pathophysiology, no non-invasive tools exist to measure this system in patients. The cystine/glutamate antiporter system x(c)(-) maintains the balance between intracellu...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: McCormick, Patrick N., Greenwood, Hannah E., Glaser, Matthias, Maddocks, Oliver D.K., Gendron, Thibault, Sander, Kerstin, Gowrishankar, Gayatri, Hoehne, Aileen, Zhang, Tong, Shuhendler, Adam J., Lewis, David Y., Berndt, Mathias, Koglin, Norman, Lythgoe, Mark F., Gambhir, Sanjiv S., Årstad, Erik, Witney, Timothy H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379064/
https://ncbi.nlm.nih.gov/pubmed/30401715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2634
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