Neuroimaging as a Selection Tool and Endpoint in Clinical and Pre-clinical Trials

Por Muir, Keith W., Macrae, I. Mhairi
Publicado no Transl Stroke Res (2016)

Watermaze performance after middle cerebral artery occlusion in the rat: the role of sensorimotor versus memory impairments

Por Bingham, Deborah, Martin, Stephen J, Macrae, I Mhairi, Carswell, Hilary V O
Publicado em 2012

Perfluorocarbons enhance a T(2)*-based MRI technique for identifying the penumbra in a rat model of acute ischemic stroke

Por Deuchar, Graeme A, Brennan, David, Griffiths, Hugh, Macrae, I  Mhairi, Santosh, Celestine
Publicado em 2013

The influence of gender on ‘tissue at risk’ in acute stroke: A diffusion-weighted magnetic resonance imaging study in a rat model of focal cerebral ischaemia

Por Baskerville, Tracey A, Macrae, I Mhairi, Holmes, William M, McCabe, Christopher
Publicado no J Cereb Blood Flow Metab (2015)

Differences in the Evolution of the Ischemic Penumbra in Stroke-Prone Spontaneously Hypertensive and Wistar-Kyoto Rats

Por McCabe, Christopher, Gallagher, Lindsay, Gsell, Willy, Graham, Delyth, Dominiczak, Anna F., Macrae, I. Mhairi
Publicado em 2009

Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with (99m)Tc-HMPAO CBF autoradiography in a rat stroke model

Por Baskerville, Tracey A, McCabe, Christopher, Weir, Christopher J, Macrae, I Mhairi, Holmes, William M
Publicado em 2012

Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods

Por Reid, Emma, Graham, Delyth, Lopez-Gonzalez, M Rosario, Holmes, William M, Macrae, I Mhairi, McCabe, Christopher
Publicado em 2012

Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time

Por Wetterling, Friedrich, Gallagher, Lindsay, Mullin, Jim, Holmes, William M, McCabe, Chris, Macrae, I Mhairi, Fagan, Andrew J
Publicado no J Cereb Blood Flow Metab (2015)

Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T(2)(*)-weighted MRI in a rat stroke model

Por Baskerville, Tracey A, Deuchar, Graeme A, McCabe, Christopher, Robertson, Craig A, Holmes, William M, Santosh, Celestine, Macrae, I Mhairi
Publicado em 2011

Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats

Por Ord, Emily N J, Shirley, Rachel, McClure, John D, McCabe, Christopher, Kremer, Eric J, Macrae, I Mhairi, Work, Lorraine M
Publicado em 2013

Oxygen challenge magnetic resonance imaging in healthy human volunteers

Por Dani, Krishna A, Moreton, Fiona C, Santosh, Celestine, Lopez, Rosario, Brennan, David, Schwarzbauer, Christian, Goutcher, Colin, O’Hare, Kevin, Macrae, I Mhairi, Muir, Keith W
Publicado no J Cereb Blood Flow Metab (2016)

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [(14)C]2-deoxyglucose autoradiography

Por Robertson, Craig A, McCabe, Christopher, Gallagher, Lindsay, Lopez-Gonzalez, Maria del Rosario, Holmes, William M, Condon, Barrie, Muir, Keith W, Santosh, Celestine, Macrae, I Mhairi
Publicado em 2011

Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion

Por Robertson, Craig A, McCabe, Christopher, Gallagher, Lindsay, Lopez-Gonzalez, Maria del Rosario, Holmes, William M, Condon, Barrie, Muir, Keith W, Santosh, Celestine, Macrae, I Mhairi
Publicado em 2011

Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging

Por Robertson, Craig A, McCabe, Christopher, Lopez-Gonzalez, M Rosario, Deuchar, Graeme A, Dani, Krishna, Holmes, William M, Muir, Keith W, Santosh, Celestine, Macrae, I Mhairi
Publicado no Int J Stroke (2015)

Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats

Por Ord, Emily N.J., Shirley, Rachel, van Kralingen, Josie C., Graves, Alice, McClure, John D., Wilkinson, Michael, McCabe, Christopher, Macrae, I. Mhairi, Work, Lorraine M.
Publicado em 2012

Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra

Por Santosh, Celestine, Brennan, David, McCabe, Christopher, Macrae, I Mhairi, Holmes, William M, Graham, David I, Gallagher, Lindsay, Condon, Barrie, Hadley, Donald M, Muir, Keith W, Gsell, Willy
Publicado em 2008

Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy

Por Murtha, Lucy A, McLeod, Damian D, Pepperall, Debbie, McCann, Sarah K, Beard, Daniel J, Tomkins, Amelia J, Holmes, William M, McCabe, Christopher, Macrae, I Mhairi, Spratt, Neil J
Publicado no J Cereb Blood Flow Metab (2015)

Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy

Por Murtha, Lucy A, McLeod, Damian D, Pepperall, Debbie, McCann, Sarah K, Beard, Daniel J, Tomkins, Amelia J, Holmes, William M, McCabe, Christopher, Macrae, I Mhairi, Spratt, Neil J
Publicado no J Cereb Blood Flow Metab (2015)

An atypical role for the myeloid receptor Mincle in central nervous system injury

Por Arumugam, Thiruma V, Manzanero, Silvia, Furtado, Milena, Biggins, Patrick J, Hsieh, Yu-Hsuan, Gelderblom, Mathias, MacDonald, Kelli PA, Salimova, Ekaterina, Li, Yu-I, Korn, Othmar, Dewar, Deborah, Macrae, I Mhairi, Ashman, Robert B, Tang, Sung-Chun, Rosenthal, Nadia A, Ruitenberg, Marc J, Magnus, Tim, Wells, Christine A
Publicado no J Cereb Blood Flow Metab (2016)

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

Por Percie du Sert, Nathalie, Alfieri, Alessio, Allan, Stuart M, Carswell, Hilary VO, Deuchar, Graeme A, Farr, Tracy D, Flecknell, Paul, Gallagher, Lindsay, Gibson, Claire L, Haley, Michael J, Macleod, Malcolm R, McColl, Barry W, McCabe, Christopher, Morancho, Anna, Moon, Lawrence DF, O’Neill, Michael J, Pérez de Puig, Isabel, Planas, Anna, Ragan, C Ian, Rosell, Anna, Roy, Lisa A, Ryder, Kathryn O, Simats, Alba, Sena, Emily S, Sutherland, Brad A, Tricklebank, Mark D, Trueman, Rebecca C, Whitfield, Lucy, Wong, Raymond, Macrae, I Mhairi
Publicado no J Cereb Blood Flow Metab (2017)