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Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy

In both the human and animal literature, it has largely been assumed that edema is the primary cause of intracranial pressure (ICP) elevation after stroke and that more edema equates to higher ICP. We recently demonstrated a dramatic ICP elevation 24 hours after small ischemic strokes in rats, with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Murtha, Lucy A, McLeod, Damian D, Pepperall, Debbie, McCann, Sarah K, Beard, Daniel J, Tomkins, Amelia J, Holmes, William M, McCabe, Christopher, Macrae, I Mhairi, Spratt, Neil J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420875/
https://ncbi.nlm.nih.gov/pubmed/25515213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.230
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