Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy

In both the human and animal literature, it has largely been assumed that edema is the primary cause of intracranial pressure (ICP) elevation after stroke and that more edema equates to higher ICP. We recently demonstrated a dramatic ICP elevation 24 hours after small ischemic strokes in rats, with...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Murtha, Lucy A, McLeod, Damian D, Pepperall, Debbie, McCann, Sarah K, Beard, Daniel J, Tomkins, Amelia J, Holmes, William M, McCabe, Christopher, Macrae, I Mhairi, Spratt, Neil J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420875/
https://ncbi.nlm.nih.gov/pubmed/25515213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.230
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