Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats

We hypothesized that targeting key points in the ischemic cascade with combined neuroglobin (Ngb) overexpression and c-jun N-terminal kinase (JNK) inhibition (SP600125) would offer greater neuroprotection than single treatment after in vitro hypoxia/reoxygenation and in a randomized, blinded in vivo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ord, Emily N J, Shirley, Rachel, McClure, John D, McCabe, Christopher, Kremer, Eric J, Macrae, I Mhairi, Work, Lorraine M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734772/
https://ncbi.nlm.nih.gov/pubmed/23632970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.70
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