Molecular mechanisms of normal and pathological aging

door López-Otín, Carlos
Gepubliceerd in Orphanet J Rare Dis (2015)

A Genomic Analysis of Rat Proteases and Protease Inhibitors

door Puente, Xose S., López-Otín, Carlos
Gepubliceerd in 2004

Proteases: Multifunctional Enzymes in Life and Disease

door López-Otín, Carlos, Bond, Judith S.
Gepubliceerd in 2008

The functional and pathologic relevance of autophagy proteases

door Fernández, Álvaro F., López-Otín, Carlos
Gepubliceerd in J Clin Invest (2015)

Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness

door Baixauli, Francesc, López-Otín, Carlos, Mittelbrunn, Maria
Gepubliceerd in 2014

Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?

door Bárcena, Clea, López-Otín, Carlos, Kroemer, Guido
Gepubliceerd in Autophagy (2018)

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

door Ugalde, Alejandro P., Mariño, Guillermo, López-Otín, Carlos
Gepubliceerd in 2010

Protective roles of matrix metalloproteinases: From mouse models to human cancer

door López-Otín, Carlos, Palavalli, Lavanya H., Samuels, Yardena
Gepubliceerd in 2009

Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer

door Quirós, Pedro M, Bárcena, Clea, López-Otín, Carlos
Gepubliceerd in Mol Cell Oncol (2014)

Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

door Carrero, Dido, Soria-Valles, Clara, López-Otín, Carlos
Gepubliceerd in Dis Model Mech (2016)

Biochemical characterization and crystalization of human Zn-α(2)-glycoprotein, a soluble class I major histocompatibility complex homolog

door Sánchez, Luis M., López-Otín, Carlos, Bjorkman, Pamela J.
Gepubliceerd in 1997

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product

door Cal, Santiago, Quesada, Víctor, Garabaya, Cecilia, López-Otín, Carlos
Gepubliceerd in 2003

New roles for OMA1 metalloprotease: From mitochondrial proteostasis to metabolic homeostasis

door Quirós, Pedro M., Ramsay, Andrew J., López-Otín, Carlos
Gepubliceerd in 2013

Reprogramming aging through DOT1L inhibition

door Soria-Valles, Clara, Osorio, Fernando G, López-Otín, Carlos
Gepubliceerd in Cell Cycle (2015)

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

door Llamazares, María, Cal, Santiago, Quesada, Víctor, López-Otín, Carlos
Gepubliceerd in J Biol Chem (2018)

Wheat Inhibitors of Heterologous α-Amylases : Characterization of Major Components from the Monomeric Class

door Gomez, Luis, Sanchez-Monge, Rosa, Lopez-Otín, Carlos, Salcedo, Gabriel
Gepubliceerd in 1991

Protease Addiction and Synthetic Lethality in Cancer

door Freije, José M. P., Fraile, Julia M., López-Otín, Carlos
Gepubliceerd in 2011

NF-κB in premature aging

door Osorio, Fernando G., López-Otín, Carlos, Freije, José M. P.
Gepubliceerd in 2012

The novel tumor suppressor AIRAPL regulates IGF1R proteostasis

door Osorio, Fernando G., Freije, José M. P., López-Otín, Carlos
Gepubliceerd in Cell Cycle (2016)

Carbotoxicity—Noxious Effects of Carbohydrates

door Kroemer, Guido, López-Otín, Carlos, Madeo, Frank, de Cabo, Rafael
Gepubliceerd in Cell (2018)