Reprogramming aging through DOT1L inhibition

Yazar: Soria-Valles, Clara, Osorio, Fernando G, López-Otín, Carlos
Yayımlandı Cell Cycle (2015)

NF-κB in premature aging

Yazar: Osorio, Fernando G., López-Otín, Carlos, Freije, José M. P.
Baskı/Yayın Bilgisi 2012

Luminescence-based in vivo monitoring of NF-κB activity through a gene delivery approach

Yazar: Osorio, Fernando G, de la Rosa, Jorge, Freije, José MP
Baskı/Yayın Bilgisi 2013

The novel tumor suppressor AIRAPL regulates IGF1R proteostasis

Yazar: Osorio, Fernando G., Freije, José M. P., López-Otín, Carlos
Yayımlandı Cell Cycle (2016)

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

Yazar: Mariño, Guillermo, Ugalde, Alejandro P., Fernández, Álvaro F., Osorio, Fernando G., Fueyo, Antonio, Freije, José M. P., López-Otín, Carlos
Baskı/Yayın Bilgisi 2010

Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver

Yazar: Whitton, Holly, Singh, Larry N., Patrick, Marissa A., Price, Andrew J., Osorio, Fernando G., López‐Otín, Carlos, Bochkis, Irina M.
Yayımlandı Aging Cell (2018)

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

Yazar: Osorio, Fernando G., Bárcena, Clea, Soria-Valles, Clara, Ramsay, Andrew J., de Carlos, Félix, Cobo, Juan, Fueyo, Antonio, Freije, José M.P., López-Otín, Carlos
Baskı/Yayın Bilgisi 2012

Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenoc...

Yazar: Centeno, Irene, Blay, Pilar, Santamaría, Iñigo, Astudillo, Aurora, Pitiot, Ana S, Osorio, Fernando G, González-Arriaga, Patricia, Iglesias, Fernando, Menéndez, Primitiva, Tardón, Adonina, Freije, Jose M, Balbín, Milagros
Baskı/Yayın Bilgisi 2011

Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid

Yazar: Gutiérrez-Fernández, Ana, Soria-Valles, Clara, Osorio, Fernando G, Gutiérrez-Abril, Jesús, Garabaya, Cecilia, Aguirre, Alina, Fueyo, Antonio, Fernández-García, María Soledad, Puente, Xose S, López-Otín, Carlos
Yayımlandı EMBO J (2015)

Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis

Yazar: Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben
Yayımlandı Cell Rep (2018)

Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome

Yazar: Santiago-Fernández, Olaya, Osorio, Fernando G., Quesada, Víctor, Rodríguez, Francisco, Basso, Sammy, Maeso, Daniel, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Folgueras, Alicia R., Freije, José M. P., López-Otín, Carlos
Yayımlandı Nat Med (2019)

An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells

Yazar: Bowling, Sarah, Sritharan, Duluxan, Osorio, Fernando G., Nguyen, Maximilian, Cheung, Priscilla, Rodriguez-Fraticelli, Alejo, Patel, Sachin, Yuan, Wei-Chien, Fujiwara, Yuko, Li, Bin E., Orkin, Stuart H., Hormoz, Sahand, Camargo, Fernando D.
Yayımlandı Cell (2020)

An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

Yazar: Bowling, Sarah, Sritharan, Duluxan, Osorio, Fernando G., Nguyen, Maximilian, Cheung, Priscilla, Rodriguez-Fraticelli, Alejo, Patel, Sachin, Yuan, Wei-Chien, Fujiwara, Yuko, Li, Bin E., Orkin, Stuart H., Hormoz, Sahand, Camargo, Fernando D.
Yayımlandı Cell (2020)

Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome

Yazar: Puente, Xose S., Quesada, Victor, Osorio, Fernando G., Cabanillas, Rubén, Cadiñanos, Juan, Fraile, Julia M., Ordóñez, Gonzalo R., Puente, Diana A., Gutiérrez-Fernández, Ana, Fanjul-Fernández, Miriam, Lévy, Nicolas, Freije, José M.P., López-Otín, Carlos
Baskı/Yayın Bilgisi 2011

Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion

Yazar: de la Rosa, Jorge, Freije, José M. P., Cabanillas, Rubén, Osorio, Fernando G., Fraga, Mario F., Fernández-García, M. Soledad, Rad, Roland, Fanjul, Víctor, Ugalde, Alejandro P., Liang, Qi, Prosser, Haydn M., Bradley, Allan, Cadiñanos, Juan, López-Otín, Carlos
Baskı/Yayın Bilgisi 2013

Cardiac electrical defects in progeroid mice and Hutchinson–Gilford progeria syndrome patients with nuclear lamina alterations

Yazar: Rivera-Torres, José, Calvo, Conrado J., Llach, Anna, Guzmán-Martínez, Gabriela, Caballero, Ricardo, González-Gómez, Cristina, Jiménez-Borreguero, Luis J., Guadix, Juan A., Osorio, Fernando G., López-Otín, Carlos, Herraiz-Martínez, Adela, Cabello, Nuria, Vallmitjana, Alex, Benítez, Raul, Gordon, Leslie B., Jalife, José, Pérez-Pomares, José M., Tamargo, Juan, Delpón, Eva, Hove-Madsen, Leif, Filgueiras-Rama, David, Andrés, Vicente
Yayımlandı Proc Natl Acad Sci U S A (2016)