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Protease Addiction and Synthetic Lethality in Cancer
The “oncogene addiction” concept refers to the dependence of cancer cells on the function of the oncogenes responsible for their transformed phenotype, while the term “non-oncogene addiction” has been introduced to define the exacerbated necessity of the normal function of non-mutated genes. In this...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356009/ https://ncbi.nlm.nih.gov/pubmed/22655236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00025 |
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