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Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a reduced capability to regenerate tissue. In recent y...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Carrero, Dido, Soria-Valles, Clara, López-Otín, Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958309/
https://ncbi.nlm.nih.gov/pubmed/27482812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024711
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