Loading...

Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

Ageing is a process that inevitably affects most living organisms and involves the accumulation of macromolecular damage, genomic instability and loss of heterochromatin. Together, these alterations lead to a decline in stem cell function and to a reduced capability to regenerate tissue. In recent y...

Full description

Saved in:
Bibliographic Details
Published in:Dis Model Mech
Main Authors: Carrero, Dido, Soria-Valles, Clara, López-Otín, Carlos
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958309/
https://ncbi.nlm.nih.gov/pubmed/27482812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024711
Tags: Add Tag
No Tags, Be the first to tag this record!