Molecular mechanisms of normal and pathological aging

di López-Otín, Carlos
Pubblicato in Orphanet J Rare Dis (2015)

A Genomic Analysis of Rat Proteases and Protease Inhibitors

di Puente, Xose S., López-Otín, Carlos
Pubblicazione 2004

Proteases: Multifunctional Enzymes in Life and Disease

di López-Otín, Carlos, Bond, Judith S.
Pubblicazione 2008

The functional and pathologic relevance of autophagy proteases

di Fernández, Álvaro F., López-Otín, Carlos
Pubblicato in J Clin Invest (2015)

Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness

di Baixauli, Francesc, López-Otín, Carlos, Mittelbrunn, Maria
Pubblicazione 2014

Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?

di Bárcena, Clea, López-Otín, Carlos, Kroemer, Guido
Pubblicato in Autophagy (2018)

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

di Ugalde, Alejandro P., Mariño, Guillermo, López-Otín, Carlos
Pubblicazione 2010

Protective roles of matrix metalloproteinases: From mouse models to human cancer

di López-Otín, Carlos, Palavalli, Lavanya H., Samuels, Yardena
Pubblicazione 2009

Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer

di Quirós, Pedro M, Bárcena, Clea, López-Otín, Carlos
Pubblicato in Mol Cell Oncol (2014)

Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells

di Carrero, Dido, Soria-Valles, Clara, López-Otín, Carlos
Pubblicato in Dis Model Mech (2016)

Biochemical characterization and crystalization of human Zn-α(2)-glycoprotein, a soluble class I major histocompatibility complex homolog

di Sánchez, Luis M., López-Otín, Carlos, Bjorkman, Pamela J.
Pubblicazione 1997

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product

di Cal, Santiago, Quesada, Víctor, Garabaya, Cecilia, López-Otín, Carlos
Pubblicazione 2003

New roles for OMA1 metalloprotease: From mitochondrial proteostasis to metabolic homeostasis

di Quirós, Pedro M., Ramsay, Andrew J., López-Otín, Carlos
Pubblicazione 2013

Reprogramming aging through DOT1L inhibition

di Soria-Valles, Clara, Osorio, Fernando G, López-Otín, Carlos
Pubblicato in Cell Cycle (2015)

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

di Llamazares, María, Cal, Santiago, Quesada, Víctor, López-Otín, Carlos
Pubblicato in J Biol Chem (2018)

Wheat Inhibitors of Heterologous α-Amylases : Characterization of Major Components from the Monomeric Class

di Gomez, Luis, Sanchez-Monge, Rosa, Lopez-Otín, Carlos, Salcedo, Gabriel
Pubblicazione 1991

Protease Addiction and Synthetic Lethality in Cancer

di Freije, José M. P., Fraile, Julia M., López-Otín, Carlos
Pubblicazione 2011

NF-κB in premature aging

di Osorio, Fernando G., López-Otín, Carlos, Freije, José M. P.
Pubblicazione 2012

The novel tumor suppressor AIRAPL regulates IGF1R proteostasis

di Osorio, Fernando G., Freije, José M. P., López-Otín, Carlos
Pubblicato in Cell Cycle (2016)

Carbotoxicity—Noxious Effects of Carbohydrates

di Kroemer, Guido, López-Otín, Carlos, Madeo, Frank, de Cabo, Rafael
Pubblicato in Cell (2018)